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Protein Alignment gro and WDR5B

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_061942.2	Gene:	WDR5B / 54554	HGNCID:	17826	Length:	330	Species:	Homo sapiens

Alignment Length:	369	Identity:	80/369 - (21%)
Similarity:	130/369 - (35%)	Gaps:	93/369 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 MPYDPHAHVRTNGIPHPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVGIPRHARQINTL-SH 443
            :|.:|:..::...:.|..|::..|    |..|||.....   ..|.|:.:......:...|| .|
Human    25 VPENPNYALKCTLVGHTEAVSSVK----FSPNGEWLASS---SADRLIIIWGAYDGKYEKTLYGH 82

  Fly   444 G-EVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQ----RDNYIRSVKLLPDGR 503
            . |:......|:.::.|.......:|:||: :.|.        ||:    ..||:......|...
Human    83 NLEISDVAWSSDSSRLVSASDDKTLKLWDV-RSGK--------CLKTLKGHSNYVFCCNFNPPSN 138

  Fly   504 TLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCS--------DGNIAV 560
            .:|.|.....:.||::.:.    |...|.:|.:      .|.|.|.|:|..        ||...:
Human   139 LIISGSFDETVKIWEVKTG----KCLKTLSAHS------DPVSAVHFNCSGSLIVSGSYDGLCRI 193

  Fly   561 WD-LHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLG 624
            || ...:.|...........|.:..||:|..:.|..||||::.||...||.|:.:
Human   194 WDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTY---------- 248

  Fly   625 YCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPY 689
               ||                 .|.:||       |:.:......|||.||..:|||:..|.
Human   249 ---TG-----------------HKNEKY-------CIFANFSVTGGKWIVSGSEDNLVYIWN--- 283

  Fly   690 GASIFQSKE--------TSSVLSCDISTDDKYIVTGSGDKKATV 725
                .|:||        |..|:|......:..|.:.:.:...|:
Human   284 ----LQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTI 323

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.