DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment gro and taf5l

DIOPT Version :9

Sequence 1:NP_996298.1 Gene:gro / 43162 FlyBaseID:FBgn0001139 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_001006779.1 Gene:taf5l / 448469 XenbaseID:XB-GENE-998039 Length:588 Species:Xenopus tropicalis


Alignment Length:357 Identity:75/357 - (21%)
Similarity:127/357 - (35%) Gaps:114/357 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   471 DISQP--GNKNPVSQL-DCLQR-------------------DNYIRSVKLLPDGRTLIVGGEASN 513
            |:..|  .|:..:.|| ||:::                   :..:.:.::.||.|.|..|.::|.
 Frog   228 DVPTPILQNEAALDQLQDCIKKVKDGPPSLTTISFYAFYNTEQLLNTAEISPDSRLLAAGFDSSC 292

  Fly   514 LSIWDLASPTPRIKAE-----LTSAAPACYALAISPDS-----------------KVCF------ 550
            :.:|.|.|  .::|||     ::....||..|....|.                 :.||      
 Frog   293 VKLWSLKS--KKLKAEPHRVDVSRIRLACDVLEEEEDEQAGTEMKILRGHSGPVYRTCFLSDSSG 355

  Fly   551 --SCCSDGNIAVWDLH---NEIL---------------------------------------VRQ 571
              ||..|.:|..|:|.   |.:|                                       :|.
 Frog   356 LLSCSEDTSIRYWNLENFTNTVLYQGHAHPVWDLDVSPCSLFFASASHDRTGRLWCFDRTFPLRI 420

  Fly   572 FQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQ---IFSLGYCPTGDWLA 633
            :.||.....||...|:.:.|.||..|.|||.|..::|..::.  |:..   :.:|.:.|.|.:||
 Frog   421 YAGHLSDVDCIKFHPNSNYLATGSTDKTVRLWSTQQGNSVRL--FTGHRGPVLALAFSPNGKYLA 483

  Fly   634 VGMENSHVEVLHASKPDKY-QLHLHESCVLSLRFAACGKWFVSTGKDNLLNAW-------RTPYG 690
            ...|:..:::...:....| :|..|...:.||.|:.......|...||.:..|       .||..
 Frog   484 SAGEDQRLKLWDLASGTLYKELRGHTDNISSLTFSPDSSLIASASMDNSVRVWDIRNSYCNTPSD 548

  Fly   691 ASIFQ-----SKETSSVLSCDISTDDKYIVTG 717
            .|..:     :.:||::||......:..:|||
 Frog   549 GSSSELVGVYTGQTSNILSVQFMACNLLMVTG 580

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
groNP_996298.1 TLE_N 11..124 CDD:397828
WD40 442..727 CDD:238121 75/357 (21%)
WD40 repeat 447..486 CDD:293791 5/17 (29%)
WD40 repeat 494..532 CDD:293791 12/42 (29%)
WD40 repeat 537..573 CDD:293791 14/102 (14%)
WD40 repeat 580..615 CDD:293791 12/34 (35%)
WD40 repeat 620..653 CDD:293791 7/33 (21%)
WD40 repeat 661..695 CDD:293791 10/40 (25%)
WD40 repeat 702..726 CDD:293791 5/16 (31%)
taf5lNP_001006779.1 TAF5_NTD2 69..201 CDD:176269
WD40 <256..406 CDD:225201 26/151 (17%)
WD40 repeat 274..339 CDD:293791 16/66 (24%)
WD40 333..580 CDD:238121 50/248 (20%)
WD40 repeat 345..381 CDD:293791 10/35 (29%)
WD40 repeat 386..422 CDD:293791 1/35 (3%)
WD40 repeat 429..464 CDD:293791 12/36 (33%)
WD40 repeat 470..506 CDD:293791 7/35 (20%)
WD40 repeat 512..559 CDD:293791 10/46 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.