Protein Alignment gro and gnb5b

DIOPT Version :9

• Sequence 1: NP_996298.1
• Gene: gro / 43162
• FlyBaseID: FBgn0001139
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_957040.1
• Gene: gnb5b / 393719
• ZFINID: ZDB-GENE-040426-1712
• Length: 395
• Species: Danio rerio
• Alignment Length: 304
• Identity: 72/304 - (23%)
• Similarity: 129/304 - (42%)
• Gaps: 33/304 - (10%)

  Fly   443 HG-EVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLI 506
            || :|:|.....:..:.|.:...|.|.||| :...||.....:.|    .::.:....|.|..:.
Zfish   104 HGNKVLCMDWCRDKRRIVSSSQDGKVIVWD-AYTTNKEHAVTMPC----TWVMACAYAPSGCAVA 163

  Fly   507 VGGEASNLSIW--------DLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDL 563
            .||..:..|::        :|||....: |..|:...:|   :.:.......:...||..|:||:
Zfish   164 CGGLDNKCSVYPLSLDKNENLASKKKSV-AMHTNYLSSC---SFTKSDMQILTSSGDGTCALWDV 224

  Fly   564 HNEILVRQFQGHTDGASCIDISPD--GSRLWTGGLDNTVRSWDLREGRQLQQ---HDFSSQIFSL 623
            .:..|::.|.||:.....:|::|.  ||...:||.|.....||:|.|:.:|.   ||  |.|.|:
Zfish   225 ESGQLLQSFHGHSADVLSLDLAPSETGSTFVSGGCDKKANVWDMRSGQNVQSFETHD--SDINSV 287

  Fly   624 GYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVL---SLRFAACGKWFVSTGKDNLLNAW 685
            .|.|:||..|.|.:::...:.......:..::..:|.:.   |:.|:..|:...:...|..:|.|
Zfish   288 KYYPSGDAFASGSDDATCRLYDLRADREVAIYSKDSIIFGASSVDFSLSGRLLFAGYNDYNINVW 352

  Fly   686 RTPYG---ASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVY 726
            ....|   |.:|..:...|.:.  :|.|.....:||.|....::
Zfish   353 DVLKGTRVAILFGHENRVSTVR--VSPDGTAFCSGSWDNTLRIW 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	72/304 (24%)
		WD40 repeat	447..486	CDD:293791	9/38 (24%)
		WD40 repeat	494..532	CDD:293791	9/45 (20%)
		WD40 repeat	537..573	CDD:293791	7/35 (20%)
		WD40 repeat	580..615	CDD:293791	12/39 (31%)
		WD40 repeat	620..653	CDD:293791	8/32 (25%)
		WD40 repeat	661..695	CDD:293791	8/39 (21%)
		WD40 repeat	702..726	CDD:293791	5/23 (22%)
gnb5b	NP_957040.1	WD40	98..395	CDD:238121	72/304 (24%)
		WD 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	103..142		12/38 (32%)
		WD40 repeat	108..145	CDD:293791	10/37 (27%)
		WD 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	145..184		6/42 (14%)
		WD40 repeat	151..193	CDD:293791	8/42 (19%)
		WD 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	193..234		8/43 (19%)
		WD40 repeat	198..234	CDD:293791	7/38 (18%)
		WD 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	235..276		13/40 (33%)
		WD40 repeat	241..278	CDD:293791	12/36 (33%)
		WD 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	279..318		11/40 (28%)
		WD40 repeat	284..320	CDD:293791	8/35 (23%)
		WD 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	320..362		8/41 (20%)
		WD40 repeat	328..364	CDD:293791	8/35 (23%)
		WD 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00221	365..395		6/32 (19%)
		WD40 repeat	370..394	CDD:293791	6/25 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910