Protein Alignment gro and tle5

DIOPT Version :10

• Sequence 1: NP_996298.1
• Gene: gro / 43162
• FlyBaseID: FBgn0001139
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_956717.1
• Gene: tle5 / 393395
• ZFINID: ZDB-GENE-040426-1409
• Length: 197
• Species: Danio rerio
• Alignment Length: 243
• Identity: 103/243 - (42%)
• Similarity: 136/243 - (55%)
• Gaps: 47/243 - (19%)

  Fly     1 MYPSPVRHPAAGGPPPQGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVM 65
            |:|.. ||.|:     ...:|||.:|:.:|||:||.||||||||:||||:||::||:||||||:|
Zfish     2 MFPQS-RHSAS-----SQQLKFTTSDSCDRIKDEFQFLQAQYHSLKLECDKLASEKSEMQRHYIM 60

  Fly    66 YYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGHQQQ 130
            |||||||||:|||||.||.||||.:..|:||:|..:||||||.|:|||||||..|:|.||..|.|
Zfish    61 YYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTPPEMNSIIRQQLQ 125

  Fly   131 HGIQQLLQQIHAQQVPGGPPQPMGALNPFGALGATMGLPHGPQGLLNKPPEHHRPDIKPTGLEGP 195
               ...|.|:....:| ..|.|:|...|.|....|     ...||.:              |...
Zfish   126 ---AHQLSQLQGLALP-MTPLPLGLSQPAGLPAVT-----SSSGLFS--------------LSSI 167

  Fly   196 AAAEERLRNSVSPADREKYRTRSPLDIENDSKRRKDEKLQEDEGEKSD 243
            .|::.:|..                  |:.|.|...:..:|::|:|||
Zfish   168 LASQAQLAK------------------EDKSTRETSDSHREEDGDKSD 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	20..124	CDD:461094	72/103 (70%)
		WD40	<443..728	CDD:441893
		WD40 repeat	447..486	CDD:293791
		WD40 repeat	494..532	CDD:293791
		WD40 repeat	537..573	CDD:293791
		WD40 repeat	580..615	CDD:293791
		WD40 repeat	620..653	CDD:293791
		WD40 repeat	661..695	CDD:293791
		WD40 repeat	702..726	CDD:293791
tle5	NP_956717.1	TLE_N	15..129	CDD:461094	76/116 (66%)