DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gro and AgaP_AGAP007626

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	XP_564611.3	Gene:	AgaP_AGAP007626 / 3290403	VectorBaseID:	AGAP007626	Length:	336	Species:	Anopheles gambiae

Alignment Length:	288	Identity:	65/288 - (22%)
Similarity:	122/288 - (42%)	Gaps:	34/288 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   458 YVYTGG-KGCVKVWDISQPGNKNPVSQLDCLQRDNY------IRSVKLLPDGRTLIVGGEASNLS 515
            ::.||| ...||:||:....:|..:       |:.:      :.||.:...|..:......|:|.
Mosquito    59 FIVTGGVDDTVKIWDVLPDRSKFKL-------RNTFTGHSLGVVSVDVSTSGEVIASSSLDSSLC 116

  Fly   516 IWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLH----NEILVRQFQGHT 576
            ||  .:.|.::..:::......:.:|.||..|...|...:|.|:::.:.    .::|..|
Mosquito   117 IW--KAETGQLMNQISVGPVDLWTVAFSPCDKYIISGSHEGKISLYSVETGKAEQVLDPQ----- 174

  Fly   577 DGASCIDI--SPDGSRLWTGGLDNTVRSWDLREGR---QLQQHDFSSQIFSLGYCPTGDWLAVGM 636
            :|...:.|  ||||..:.:|.:|..:..:|:..|:   .|:.|..|  :.||.:.|....|....
Mosquito   175 NGKFTLSIAYSPDGKYIASGAIDGIINIFDVAAGKVAQTLEGHAMS--VRSLCFSPDSQMLLTAS 237

  Fly   637 ENSHVEVLHASKPDKY-QLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQ-SKET 699
            ::.|:::...:..|.. .|..|.|.|||:.|:..||.|.|:..|..:..|.......:.. ::..
Mosquito   238 DDGHMKLYDVAHSDVVGTLSGHASWVLSVSFSGDGKNFASSSSDKTVKIWNVAERQCLHTFTEHA 302

  Fly   700 SSVLSCDISTDDKYIVTGSGDKKATVYE 727
            ..|.....|.|...:::.|.||...:|:
Mosquito   303 DQVWGVRYSPDSANVISVSEDKCINMYD 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	64/286 (22%)
		WD40 repeat	447..486	CDD:293791	8/28 (29%)
		WD40 repeat	494..532	CDD:293791	8/37 (22%)
		WD40 repeat	537..573	CDD:293791	9/39 (23%)
		WD40 repeat	580..615	CDD:293791	10/39 (26%)
		WD40 repeat	620..653	CDD:293791	6/33 (18%)
		WD40 repeat	661..695	CDD:293791	10/33 (30%)
		WD40 repeat	702..726	CDD:293791	6/23 (26%)
AgaP_AGAP007626	XP_564611.3	WD40	58..>332	CDD:225201	65/288 (23%)
		WD40	58..330	CDD:238121	64/286 (22%)
		WD40 repeat	95..133	CDD:293791	8/39 (21%)
		WD40 repeat	136..172	CDD:293791	7/35 (20%)
		WD40 repeat	180..215	CDD:293791	9/34 (26%)
		WD40 repeat	221..257	CDD:293791	6/35 (17%)
		WD40 repeat	263..299	CDD:293791	10/35 (29%)
		WD40 repeat	305..329	CDD:293791	6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910