DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gro and CG2260

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_572441.1	Gene:	CG2260 / 31732	FlyBaseID:	FBgn0030000	Length:	609	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	39/163 - (23%)
Similarity:	64/163 - (39%)	Gaps:	18/163 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   455 PTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDL 519
            ||.|. ...|..|..:|  :.|     ::|.|::|.|.:..:..||....|..|..|...|..|:
  Fly   226 PTMYA-VAQKSWVYFYD--KKG-----TELHCIKRLNRVNRLDFLPYHFLLAAGNSAGYASWLDV 282

  Fly   520 ASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGN--IAVWDLHNEILVRQFQGHTDGASCI 582
            :  ...:.....:.......|..:|.:.|.  |...|.  :::|.......:.:...|:...|.:
  Fly   283 S--IGELVGNFNTGLGDIRMLRHNPRNGVL--CIGGGRGVVSMWSPKVREPLAKLLCHSTAMSAL 343

  Fly   583 DISPDGSRLWTGGLDNTVRSWDLREGRQLQQHD 615
            .:.|.|..|.|.|||..|:.||:|    :..||
  Fly   344 AVEPKGQYLVTAGLDRAVKVWDIR----MLVHD 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	39/163 (24%)
		WD40 repeat	447..486	CDD:293791	8/30 (27%)
		WD40 repeat	494..532	CDD:293791	7/37 (19%)
		WD40 repeat	537..573	CDD:293791	6/37 (16%)
		WD40 repeat	580..615	CDD:293791	12/34 (35%)
		WD40 repeat	620..653	CDD:293791
		WD40 repeat	661..695	CDD:293791
		WD40 repeat	702..726	CDD:293791
CG2260	NP_572441.1	WD40	177..398	CDD:295369	39/163 (24%)
		WD40	<181..371	CDD:225201	37/160 (23%)
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..253	CDD:293791	9/34 (26%)
		WD40 repeat	256..292	CDD:293791	7/37 (19%)
		WD40 repeat	299..334	CDD:293791	6/36 (17%)
		WD40 repeat	340..376	CDD:293791	14/37 (38%)
		BING4CT	422..500	CDD:198101
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910