DRSC/TRiP Functional Genomics Resources

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Protein Alignment gro and POC1B

DIOPT Version :9

Sequence 1:NP_996298.1 Gene:gro / 43162 FlyBaseID:FBgn0001139 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_758440.1 Gene:POC1B / 282809 HGNCID:30836 Length:478 Species:Homo sapiens


Alignment Length:259 Identity:65/259 - (25%)
Similarity:112/259 - (43%) Gaps:10/259 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   434 HARQINTLSHGEVVCAVTISNPTKYVYTGGKG-CVKVWDISQPGNKNPVSQLDCLQRDNYIRSVK 497
            |||....:.|.:||.:|..|.....:.:..:. .|::|   .|..:...|:...  ....:|||.
Human    50 HARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLW---IPDKRGKFSEFKA--HTAPVRSVD 109

  Fly   498 LLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWD 562
            ...||:.|....|..::.:|.:.  ..|....|............|||.::..||..|..|.:||
Human   110 FSADGQFLATASEDKSIKVWSMY--RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172

  Fly   563 LHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYC 626
            ..|:..|..|......|:.:|.:|.|:.:.:.|.|.||:.||:|..:.||.:. .|..:..:.:.
Human   173 TTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH 237

  Fly   627 PTGDWLAVGMENSHVEVLHASKPDK-YQLHLHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPY 689
            |:|::|.....:..:::|...:... |.|..|...|.::.|:..|:.|.|.|.|..:..|||.:
Human   238 PSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNF 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
groNP_996298.1 TLE_N 11..124 CDD:397828
WD40 442..727 CDD:238121 62/251 (25%)
WD40 repeat 447..486 CDD:293791 7/39 (18%)
WD40 repeat 494..532 CDD:293791 10/37 (27%)
WD40 repeat 537..573 CDD:293791 11/35 (31%)
WD40 repeat 580..615 CDD:293791 12/34 (35%)
WD40 repeat 620..653 CDD:293791 4/33 (12%)
WD40 repeat 661..695 CDD:293791 10/29 (34%)
WD40 repeat 702..726 CDD:293791
POC1BNP_758440.1 WD40 10..298 CDD:238121 62/254 (24%)
WD 1 16..55 3/4 (75%)
WD40 repeat 21..58 CDD:293791 3/7 (43%)
WD 2 58..99 9/43 (21%)
WD40 repeat 63..100 CDD:293791 7/39 (18%)
WD 3 101..139 9/39 (23%)
WD40 repeat 106..142 CDD:293791 10/37 (27%)
WD 4 142..181 11/38 (29%)
WD40 repeat 147..182 CDD:293791 11/34 (32%)
WD 5 183..223 12/39 (31%)
WD40 repeat 190..225 CDD:293791 12/34 (35%)
WD 6 226..265 5/38 (13%)
WD40 repeat 231..267 CDD:293791 5/35 (14%)
WD 7 268..307 11/34 (32%)
WD40 repeat 273..299 CDD:293791 8/25 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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