DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gro and SPAC959.03c

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_594170.1	Gene:	SPAC959.03c / 2543484	PomBaseID:	SPAC959.03c	Length:	520	Species:	Schizosaccharomyces pombe

Alignment Length:	287	Identity:	64/287 - (22%)
Similarity:	104/287 - (36%)	Gaps:	75/287 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   457 KYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLAS 521
            ||||        |:|       |..:::.||:|...:.::..||....|...|.|..|...|::
pombe   163 KYVY--------VYD-------NMGTEIHCLKRHIEVNALDFLPYHLLLTSIGNAGYLKYQDVS- 211

  Fly   522 PTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISP 586
             |.::.||..:...|.:.|..:|.:.|.....::|.:.:|...:...:.:...|......:.::.
pombe   212 -TGQLVAEHRTGMGASHVLHQNPHNAVEHVGHANGQVTLWSPSSTTPLVKMLTHRGPVRDLAVNR 275

  Fly   587 DGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPT---------GDWLAVGMENSHV- 641
            ||..:.|.|.|:.::.||||..::|..:          |.||         ...||||. ..|.
pombe   276 DGRYMVTAGADSLLKVWDLRTYKELHSY----------YTPTPAQRLTLSDRGLLAVGW-GPHAT 329

  Fly   642 ---EVLHASKPDKYQLH-LHESCVLSLRFAACGKWFVSTGKDNLLNAWRTPYG--ASIFQSKETS 700
               :.|...:...|..| |..|.|:.|.:.                    ||.  ..|..:|...
pombe   330 IWKDALRTKQNFPYMNHLLPSSSVVDLHYC--------------------PYEDILGIGHAKGFE 374

  Fly   701 SVLSCDISTDDKYIVTGSGDKKATVYE 727
            |:           ||.|||:.....||
pombe   375 SI-----------IVPGSGEPNYDSYE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	62/285 (22%)
		WD40 repeat	447..486	CDD:293791	7/28 (25%)
		WD40 repeat	494..532	CDD:293791	10/37 (27%)
		WD40 repeat	537..573	CDD:293791	5/35 (14%)
		WD40 repeat	580..615	CDD:293791	10/34 (29%)
		WD40 repeat	620..653	CDD:293791	9/45 (20%)
		WD40 repeat	661..695	CDD:293791	5/35 (14%)
		WD40 repeat	702..726	CDD:293791	5/23 (22%)
SPAC959.03c	NP_594170.1	WD40	105..>303	CDD:295369	37/156 (24%)
		WD40 repeat	105..138	CDD:293791
		WD40	<110..376	CDD:225201	56/260 (22%)
		WD40 repeat	146..182	CDD:293791	10/33 (30%)
		WD40 repeat	184..217	CDD:293791	8/34 (24%)
		WD40 repeat	225..263	CDD:293791	6/37 (16%)
		WD40 repeat	268..303	CDD:293791	10/34 (29%)
		BING4CT	342..420	CDD:285375	18/80 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910