DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gro and cpc2

DIOPT Version :9

Sequence 1:	NP_996298.1	Gene:	gro / 43162	FlyBaseID:	FBgn0001139	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_593770.1	Gene:	cpc2 / 2543298	PomBaseID:	SPAC6B12.15	Length:	314	Species:	Schizosaccharomyces pombe

Alignment Length:	314	Identity:	75/314 - (23%)
Similarity:	121/314 - (38%)	Gaps:	52/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   409 HMNGEGSLQPVPFPPDAL------------------VGVGIPRHARQINTLSHGEVVCAVTISNP 455
            |.....||...|..||.|                  |..|:.:  |::...||....||::..:.
pombe    14 HSGWVTSLSTAPENPDILLSGSRDKSIILWNLVRDDVNYGVAQ--RRLTGHSHFVSDCALSFDSH 76

  Fly   456 TKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQR----DNYIRSVKLLPDGRTLIVGGEASNLSI 516
            .....:..| .:::||:.:.         :|..:    .:.:.||.:.||.|.::.|.....:.|
pombe    77 YALSASWDK-TIRLWDLEKG---------ECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKI 131

  Fly   517 WDLASPTPRIKAELTSAA----PACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTD 577
            |::..   ..|..:|...    .:|...:.:||:....|...|..:.||||....|.....|||.
pombe   132 WNIIG---NCKYTITDGGHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFSLRTSHYGHTG 193

  Fly   578 GASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWL--AVGMENSH 640
            ..|.:.||||||...:||.|.|:..|||.|...|...:..:.|.:|.:.|...||  |.|.....
pombe   194 YVSAVTISPDGSLCASGGRDGTLMLWDLNESTHLYSLEAKANINALVFSPNRYWLCAATGSSIRI 258

  Fly   641 VEVLHASKPDKYQLHL--------HESCVLSLRFAACGKWFVSTGKDNLLNAWR 686
            .::....|.|:..:..        ...|: ||.::..|:...|...|||:..|:
pombe   259 FDLETQEKVDELTVDFVGVGKKSSEPECI-SLTWSPDGQTLFSGWTDNLIRVWQ 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	65/263 (25%)
		WD40 repeat	447..486	CDD:293791	5/38 (13%)
		WD40 repeat	494..532	CDD:293791	9/37 (24%)
		WD40 repeat	537..573	CDD:293791	10/35 (29%)
		WD40 repeat	580..615	CDD:293791	16/34 (47%)
		WD40 repeat	620..653	CDD:293791	9/34 (26%)
		WD40 repeat	661..695	CDD:293791	8/26 (31%)
		WD40 repeat	702..726	CDD:293791
cpc2	NP_593770.1	WD40	7..311	CDD:238121	74/312 (24%)
		WD40	<7..310	CDD:225201	74/311 (24%)
		WD40 repeat	18..61	CDD:293791	9/44 (20%)
		WD40 repeat	67..103	CDD:293791	6/45 (13%)
		WD40 repeat	108..144	CDD:293791	9/38 (24%)
		WD40 repeat	152..189	CDD:293791	10/36 (28%)
		WD40 repeat	195..231	CDD:293791	16/35 (46%)
		WD40 repeat	236..275	CDD:293791	9/38 (24%)
		WD40 repeat	286..310	CDD:293791	8/24 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910