DRSC/TRiP Functional Genomics Resources

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Protein Alignment gro and pfs-2

DIOPT Version :9

Sequence 1:NP_996298.1 Gene:gro / 43162 FlyBaseID:FBgn0001139 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_001380152.1 Gene:pfs-2 / 175092 WormBaseID:WBGene00011051 Length:809 Species:Caenorhabditis elegans


Alignment Length:367 Identity:84/367 - (22%)
Similarity:129/367 - (35%) Gaps:88/367 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   394 PHPSALTGGKP-AYSFHMNGEGSLQPVPFPPDALVGVGIPRHARQ--INTLSHGEVVCAVTISNP 455
            |..|::...:| ..:.|.:.....|.....|| ::|.|..|..|:  .|...|.:.|..|.....
 Worm    20 PSTSSMQNSQPRIMNNHHHPHNRFQREHVMPD-VMGDGPGRRLRKNVANVRRHVDYVSTVLNHCE 83

  Fly   456 TKYVYTGGKGCVKVWDI-----SQPGNKNPVSQLDCLQRDNYIR-----------SVKLLPDGRT 504
            .:....|.:..::..||     :.|.:..|...:||: ...:||           ||...|:|:.
 Worm    84 NRLWQYGKQRILQQPDILYQQYAVPADSTPDVPVDCI-LTKFIRTAMNKVKCPVYSVCWSPEGKR 147

  Fly   505 LIVGGEASNLSIWD---------LASPTPRIKA--------ELTSAAPACY-------------- 538
            ||.|.:....::|:         |.:....|:|        .|.||....|              
 Worm   148 LITGCQTGEFTLWNGTAFNFETILQAHDSAIRALKWASNEQWLLSADQGGYVKYWQPNMNNAHMF 212

  Fly   539 ---------ALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTG 594
                     .||.:|......:...||...|||.......|..:||.....|||..|....:.||
 Worm   213 SAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATG 277

  Fly   595 GLD--NTVRSWDLREG---RQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDK--- 651
            ..|  ..|:.||.:.|   ..||:|  .|.:.::.:...|:||..| ...|:..::..:..|   
 Worm   278 SRDTQQPVKIWDPKSGSCLATLQEH--KSSVMAVEFNKNGNWLLTG-GRDHLVKMYDIRMMKEMR 339

  Fly   652 -YQLHLHESCVLSLRFAACGKW-------FVSTGKDNLLNAW 685
             |:.|..|  |:||      .|       |||.|.|..:..|
 Worm   340 TYRAHKKE--VISL------AWHPIHEGLFVSGGGDGSIVYW 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
groNP_996298.1 TLE_N 11..124 CDD:397828
WD40 442..727 CDD:238121 72/316 (23%)
WD40 repeat 447..486 CDD:293791 7/43 (16%)
WD40 repeat 494..532 CDD:293791 13/65 (20%)
WD40 repeat 537..573 CDD:293791 10/58 (17%)
WD40 repeat 580..615 CDD:293791 13/39 (33%)
WD40 repeat 620..653 CDD:293791 6/36 (17%)
WD40 repeat 661..695 CDD:293791 10/32 (31%)
WD40 repeat 702..726 CDD:293791
pfs-2NP_001380152.1 WD40 135..417 CDD:238121 60/250 (24%)
WD40 repeat 136..173 CDD:293791 9/36 (25%)
WD40 repeat 179..215 CDD:293791 5/35 (14%)
WD40 repeat 220..256 CDD:293791 9/35 (26%)
WD40 repeat 263..300 CDD:293791 11/36 (31%)
WD40 repeat 306..342 CDD:293791 6/36 (17%)
WD40 repeat 348..385 CDD:293791 10/32 (31%)
WD40 repeat 392..416 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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