DRSC/TRiP Functional Genomics Resources

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Protein Alignment gro and Gnb5

DIOPT Version :9

Sequence 1:NP_996298.1 Gene:gro / 43162 FlyBaseID:FBgn0001139 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_034443.1 Gene:Gnb5 / 14697 MGIID:101848 Length:395 Species:Mus musculus


Alignment Length:300 Identity:73/300 - (24%)
Similarity:127/300 - (42%) Gaps:25/300 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   443 HG-EVVCAVTISNPTKYVYTGGKGCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLI 506
            || :|:|.....:..:.|.:...|.|.||| |...||.....:.|    .::.:....|.|..:.
Mouse   104 HGNKVLCMDWCKDKRRIVSSSQDGKVIVWD-SFTTNKEHAVTMPC----TWVMACAYAPSGCAIA 163

  Fly   507 VGGEASNLSIWDLA-SPTPRIKAELTSAA------PACYALAISPDSKVCFSCCSDGNIAVWDLH 564
            .||..:..|::.|. .....:.|:..|.|      .||   :.:.......:...||..|:||:.
Mouse   164 CGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSAC---SFTNSDMQILTASGDGTCALWDVE 225

  Fly   565 NEILVRQFQGHTDGASCIDISPD--GSRLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIFSLGYC 626
            :..|::.|.||.....|:|::|.  |:...:||.|.....||:|.|:.:|..: ..|.:.|:.|.
Mouse   226 SGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYY 290

  Fly   627 PTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVL---SLRFAACGKWFVSTGKDNLLNAWRTP 688
            |:||..|.|.:::...:.......:..::..||.:.   |:.|:..|:...:...|..:|.|...
Mouse   291 PSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVL 355

  Fly   689 YGA--SIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVY 726
            .|:  ||....| :.|.:..:|.|.....:||.|....|:
Mouse   356 KGSRVSILFGHE-NRVSTLRVSPDGTAFCSGSWDHTLRVW 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
groNP_996298.1 TLE_N 11..124 CDD:397828
WD40 442..727 CDD:238121 73/299 (24%)
WD40 repeat 447..486 CDD:293791 10/38 (26%)
WD40 repeat 494..532 CDD:293791 7/38 (18%)
WD40 repeat 537..573 CDD:293791 7/35 (20%)
WD40 repeat 580..615 CDD:293791 12/36 (33%)
WD40 repeat 620..653 CDD:293791 7/32 (22%)
WD40 repeat 661..695 CDD:293791 9/38 (24%)
WD40 repeat 702..726 CDD:293791 6/23 (26%)
Gnb5NP_034443.1 WD40 98..395 CDD:238121 73/299 (24%)
WD 1 103..142 13/38 (34%)
WD40 repeat 108..145 CDD:293791 11/37 (30%)
WD 2 145..184 7/42 (17%)
WD40 repeat 151..193 CDD:293791 8/41 (20%)
WD 3 193..234 8/43 (19%)
WD40 repeat 198..234 CDD:293791 8/38 (21%)
WD 4 236..278 13/41 (32%)
WD40 repeat 241..278 CDD:293791 12/36 (33%)
WD 5 279..318 8/38 (21%)
WD40 repeat 284..320 CDD:293791 7/35 (20%)
WD 6 320..362 9/41 (22%)
WD40 repeat 328..364 CDD:293791 9/35 (26%)
WD 7 365..394 7/29 (24%)
WD40 repeat 370..394 CDD:293791 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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