DRSC/TRiP Functional Genomics Resources

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Protein Alignment gro and Gnb1

DIOPT Version :9

Sequence 1:NP_996298.1 Gene:gro / 43162 FlyBaseID:FBgn0001139 Length:730 Species:Drosophila melanogaster
Sequence 2:NP_001153488.1 Gene:Gnb1 / 14688 MGIID:95781 Length:340 Species:Mus musculus


Alignment Length:277 Identity:61/277 - (22%)
Similarity:108/277 - (38%) Gaps:41/277 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   465 GCVKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAE 529
            |.:.:|| |...||.....|    |.:::.:....|.|..:..||..:..||::|.:....::..
Mouse    77 GKLIIWD-SYTTNKVHAIPL----RSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVS 136

  Fly   530 LTSAAPACYALAISPDSKVCFSCC------------SDGNIAVWDLHNEILVRQFQGHTDGASCI 582
            ...|....|           .|||            .|...|:||:........|.|||.....:
Mouse   137 RELAGHTGY-----------LSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSL 190

  Fly   583 DISPDGSRLWTGGLDNTVRSWDLREGRQLQQ---HDFSSQIFSLGYCPTGDWLAVGMENSHVEVL 644
            .::||.....:|..|.:.:.||:|||...|.   |:  |.|.::.:.|.|:..|.|.:::...:.
Mouse   191 SLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE--SDINAICFFPNGNAFATGSDDATCRLF 253

  Fly   645 HASKPDKYQLHLHES--C-VLSLRFAACGKWFVSTGKDNLLNAWRTPYG--ASIFQSKETSSVLS 704
            ......:...:.|::  | :.|:.|:..|:..::...|...|.|.....  |.:....:..  :|
Mouse   254 DLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR--VS 316

  Fly   705 C-DISTDDKYIVTGSGD 720
            | .::.|...:.|||.|
Mouse   317 CLGVTDDGMAVATGSWD 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
groNP_996298.1 TLE_N 11..124 CDD:397828
WD40 442..727 CDD:238121 61/277 (22%)
WD40 repeat 447..486 CDD:293791 7/20 (35%)
WD40 repeat 494..532 CDD:293791 7/37 (19%)
WD40 repeat 537..573 CDD:293791 8/47 (17%)
WD40 repeat 580..615 CDD:293791 10/37 (27%)
WD40 repeat 620..653 CDD:293791 5/32 (16%)
WD40 repeat 661..695 CDD:293791 7/35 (20%)
WD40 repeat 702..726 CDD:293791 7/20 (35%)
Gnb1NP_001153488.1 WD40 48..340 CDD:238121 61/277 (22%)
WD 1 53..83 1/5 (20%)
WD40 repeat 58..95 CDD:293791 6/18 (33%)
WD 2 95..125 8/33 (24%)
WD40 repeat 101..141 CDD:293791 7/39 (18%)
WD 3 141..170 6/39 (15%)
WD40 repeat 146..181 CDD:293791 7/34 (21%)
WD 4 182..212 7/29 (24%)
WD40 repeat 188..223 CDD:293791 10/34 (29%)
WD 5 224..254 7/31 (23%)
WD40 repeat 229..265 CDD:293791 5/35 (14%)
WD 6 268..298 6/29 (21%)
WD40 repeat 273..309 CDD:293791 7/35 (20%)
WD 7 310..340 7/26 (27%)
WD40 repeat 315..339 CDD:293791 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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