Protein Alignment gro and CFAP52

DIOPT Version :9

• Sequence 1: NP_996298.1
• Gene: gro / 43162
• FlyBaseID: FBgn0001139
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_659491.4
• Gene: CFAP52 / 146845
• HGNCID: 16053
• Length: 620
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 59/265 - (22%)
• Similarity: 98/265 - (36%)
• Gaps: 71/265 - (26%)

  Fly   438 INTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDIS------QPGNKNPVSQLDCLQ-RDNYIRS 495
            ||......|....|.|:..:.:..||:|.|:||.|.      :...|...|.:.|:: :.|....
Human   412 INNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEEC 476

  Fly   496 VKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAP-----ACYALAISPDSKVCFSCCSD 555
            |....||..:          ||||.    |::......|.     .||    .|:.....:..:|
Human   477 VTASTDGTCI----------IWDLV----RLRRNQMILANTLFQCVCY----HPEEFQIITSGTD 523

  Fly   556 GNIAVWDLHNEILVRQFQGHTDGA-SCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQ 619
            ..||.|::.:..::|:.:|...|: :.:||:.:|....|||.|:.|:.||..||
Human   524 RKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEG----------- 577

  Fly   620 IFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHESCVLSLRFAACGKWFVSTGKDNLLNA 684
                             |.:||.|.|:..            :..:|.:...::.||...|..:..
Human   578 -----------------EVTHVGVGHSGN------------ITRIRISPGNQYIVSVSADGAILR 613

  Fly   685 WRTPY 689
            |:.||
Human   614 WKYPY 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gro	NP_996298.1	TLE_N	11..124	CDD:397828
		WD40	442..727	CDD:238121	57/261 (22%)
		WD40 repeat	447..486	CDD:293791	11/44 (25%)
		WD40 repeat	494..532	CDD:293791	8/37 (22%)
		WD40 repeat	537..573	CDD:293791	8/35 (23%)
		WD40 repeat	580..615	CDD:293791	12/34 (35%)
		WD40 repeat	620..653	CDD:293791	5/32 (16%)
		WD40 repeat	661..695	CDD:293791	7/29 (24%)
		WD40 repeat	702..726	CDD:293791
CFAP52	NP_659491.4	WD40	1..405	CDD:225201
		WD 1. /evidence=ECO:0000255	62..106
		WD40 repeat	68..109	CDD:293791
		WD40	100..141	CDD:197651
		WD 2. /evidence=ECO:0000255	109..150
		WD40 repeat	114..159	CDD:293791
		WD 3. /evidence=ECO:0000255	156..195
		WD40 repeat	166..201	CDD:293791
		WD40 repeat	208..245	CDD:293791
		WD40 repeat	253..307	CDD:293791
		WD40	277..617	CDD:225201	57/262 (22%)
		WD 4. /evidence=ECO:0000255	288..327
		WD 5. /evidence=ECO:0000255	330..369
		WD40	346..615	CDD:295369	56/260 (22%)
		WD 6. /evidence=ECO:0000255	372..411
		WD40 repeat	380..414	CDD:293791	1/1 (100%)
		WD 7. /evidence=ECO:0000255	415..454		10/38 (26%)
		WD40 repeat	420..459	CDD:293791	10/38 (26%)
		WD 8. /evidence=ECO:0000255	459..498		11/52 (21%)
		WD40 repeat	465..500	CDD:293791	10/48 (21%)
		WD 9. /evidence=ECO:0000255	500..539		8/42 (19%)
		WD40 repeat	505..541	CDD:293791	8/39 (21%)
		WD 10. /evidence=ECO:0000255	543..582		14/66 (21%)
		WD40 repeat	549..584	CDD:293791	15/62 (24%)
		WD 11. /evidence=ECO:0000255	585..620		8/46 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910