Protein Alignment E(spl)m8-HLH and Hes7

DIOPT Version :9

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_149030.2
• Gene: Hes7 / 84653
• MGIID: 2135679
• Length: 225
• Species: Mus musculus
• Alignment Length: 219
• Identity: 54/219 - (24%)
• Similarity: 87/219 - (39%)
• Gaps: 59/219 - (26%)

  Fly    12 KVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGIL--RMDKAEMLESAVIFMRQQK------TP 68
            |:.||::|::||.|:|:.|:.|:.|:.|...|..:.  :::|||:||.||.::|::.      .|
Mouse    14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVP 78

  Fly    69 KKVAQEEQSLP---LDSFK-------------------------NGYMNAVNEVSRVMASTPGM- 104
            :...|:.::|.   |..|:                         :||...  :..|..|..||:
Mouse    79 RSPGQDAEALASCYLSGFRECLLRLAAFAHDASPAARSQLFSALHGYRRP--KPPRPEAVDPGLP 141

  Fly   105 ----SVDLGKSVMTHLGRVYKNLQQFHEAQSAADFIQNSMDCSSM-----DKAPLS----PASSG 156
                .:|....:   ||.........|:...:.....:...|||.     ..|||:    |....
Mouse   142 APRPPLDPASPI---LGPALHQRPPVHQGPPSPRLAWSPSHCSSRAGDSGAPAPLTGLLPPPPPP 203

  Fly   157 YHSDCDSPAPS-PQPMQQPLWRPW 179
            |..|....||| |.|   ..||||
Mouse   204 YRQDGAPKAPSLPPP---AFWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	21/62 (34%)
		ORANGE	81..125	CDD:128787	10/73 (14%)
Hes7	NP_149030.2	HLH	14..73	CDD:238036	21/58 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..225		28/109 (26%)
		WRPW motif	221..224		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830915
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740