Protein Alignment E(spl)m8-HLH and hes7

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001039166.1
• Gene: hes7 / 733997
• XenbaseID: XB-GENE-876465
• Length: 178
• Species: Xenopus tropicalis
• Alignment Length: 184
• Identity: 48/184 - (26%)
• Similarity: 87/184 - (47%)
• Gaps: 29/184 - (15%)

  Fly     8 QIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGIL--RMDKAEMLESAVIFMRQQKTPKK 70
            :.::|:.||::||:||.|:|..|:.|:..:::....:.:.  :::|||:||..|.|::.    .|
 Frog    11 EAHRKLLKPLVERRRRERINNSLEKLRIFLSQALKSEKLKNPKVEKAEILECTVQFLQS----SK 71

  Fly    71 VAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADF 135
            :..::..:....:::|:.:.:......|.|.|.::| ..|..::|....||...   ||.|..|.
 Frog    72 LVPQDGDVGNKGYQSGFQHCLETALHFMNSKPDLNV-ATKDFLSHQLSSYKPPA---EAWSPTDT 132

  Fly   136 IQNSMDCSSMDKAP-LSPASSGYHSDCDSPAP---------SPQPMQQPLWRPW 179
            .:.:......|.|| ||       |:..|.:|         |||..|  .||||
 Frog   133 PKPTPSIGYQDSAPHLS-------SNTISVSPTKTLVDGQFSPQTFQ--TWRPW 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	18/59 (31%)
		ORANGE	81..125	CDD:128787	9/43 (21%)
hes7	NP_001039166.1	bHLH-O_HES7	14..74	CDD:381468	19/63 (30%)
		Hairy_orange	84..121	CDD:462193	7/37 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..147		6/27 (22%)
		WRPW motif. /evidence=ECO:0000255	174..177		2/2 (100%)