Protein Alignment E(spl)m8-HLH and hes5.2

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001037974.1
• Gene: hes5.2 / 733755
• XenbaseID: XB-GENE-876635
• Length: 158
• Species: Xenopus tropicalis
• Alignment Length: 170
• Identity: 42/170 - (24%)
• Similarity: 72/170 - (42%)
• Gaps: 33/170 - (19%)

  Fly    12 KVKKPMLERQRRARMNKCLDNLKTLVAEL-RGDDGILRMDKAEMLESAVIFMRQQKTP-KKVAQE 74
            |::||::|:.||.|:|..::.||.|:..: ......::::||::||..|.::|||... |.....
 Frog    20 KLRKPVVEKMRRDRINSSIEQLKGLLETVFHKQQPNVKLEKADILEMTVTYLRQQTLQIKSEIPH 84

  Fly    75 EQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFIQNS 139
            ...:.:| :|:||.....||           :|. .|:........|.:..||...:|:......
 Frog    85 NNDIQMD-YKDGYSRCFEEV-----------IDF-LSLHQKQPETAKLISHFHSKATASSISSFP 136

  Fly   140 MDCSSMDKAPLSPASSGYHSDCDSPAPSPQPMQQPLWRPW 179
            :.||....|..:.:||.                  |||||
 Frog   137 IRCSQSKTANGTGSSSS------------------LWRPW 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	19/59 (32%)
		ORANGE	81..125	CDD:128787	9/43 (21%)
hes5.2	NP_001037974.1	bHLH-O_HES5	20..77	CDD:381467	19/56 (34%)
		ORANGE	90..128	CDD:128787	11/50 (22%)