Protein Alignment E(spl)m8-HLH and Hes3

DIOPT Version :9

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_073178.1
• Gene: Hes3 / 64628
• RGDID: 621339
• Length: 175
• Species: Rattus norvegicus
• Alignment Length: 203
• Identity: 45/203 - (22%)
• Similarity: 72/203 - (35%)
• Gaps: 69/203 - (33%)

  Fly    18 LERQRRARMNKCLDNLKTLVA-----ELRGDDGILRMDKAEMLESAVIFMRQQKTPKKVAQEEQS 77
            :|::||||:|..|:.|::|:.     ::|.    .:::||::||.:|.::|
  Rat     1 MEKKRRARINLSLEQLRSLLERHYSHQIRK----RKLEKADILELSVKYVR-------------- 47

  Fly    78 LPLDSFKNGYM------NAVNEVSRVMASTPGMSV-------DLGKSVMTHLGRVYKNLQQFHEA 129
                |.:|...      :.|:..|......||.|.       |.|......|.|...:.......
  Rat    48 ----SLQNSLQGLWLVPSGVDYPSGFRGGLPGSSQRLRPGEDDSGLRCPLLLQRRAGSTTDSANP 108

  Fly   130 QSAADFIQNSMDCSSMDKAPLSPASSGYHSDCDSPAP-------------SPQP-----MQQP-- 174
            |:|:..    ..|.....||..||  |......||.|             :|.|     .:.|
  Rat   109 QTASVL----SPCLPAIWAPGPPA--GGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRP 167

  Fly   175 ---LWRPW 179
               :||||
  Rat   168 GFRVWRPW 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	16/53 (30%)
		ORANGE	81..125	CDD:128787	11/56 (20%)
Hes3	NP_073178.1	bHLH-O_HES3	1..55	CDD:381503	18/75 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..175		12/52 (23%)
		WRPW motif	172..175		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840