Protein Alignment E(spl)m8-HLH and hey2

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_571697.2
• Gene: hey2 / 58146
• ZFINID: ZDB-GENE-000526-1
• Length: 324
• Species: Danio rerio
• Alignment Length: 205
• Identity: 56/205 - (27%)
• Similarity: 92/205 - (44%)
• Gaps: 33/205 - (16%)

  Fly     4 TTKTQIY-QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAVIFMRQ-QK 66
            ||.:|:. :|.::.::|::||.|:|..|..|:.||.......|..:::|||:|:..|..::. |.
Zfish    41 TTTSQVMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQA 105

  Fly    67 TPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGM--SVDLGKSVMTHLG------------ 117
            |..|...:..||.:|....|:...:.||:|.::|..|:  |..|...:::||.
Zfish   106 TGGKGYFDAHSLAMDFLSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSSCASQREAAAMT 170

  Fly   118 -RVYKNLQQFHEAQSA-------ADFIQN----SMDCSS--MDKAPLSPASSGYHSDCDSPAPSP 168
             .:..:.|..|....|       |.|:|.    |.:.||  :.:||...|:...|||....|||.
Zfish   171 TSIAHHQQALHPHHWAAALHPIPAAFLQQSGLPSSESSSGRLSEAPQRGAALFSHSDSALRAPST 235

  Fly   169 ---QPMQQPL 175
               .|...||
Zfish   236 GSVAPCVPPL 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	18/58 (31%)
		ORANGE	81..125	CDD:128787	11/58 (19%)
hey2	NP_571697.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		bHLH-O_HEY2	40..121	CDD:381490	24/79 (30%)
		ORANGE	119..165	CDD:128787	11/45 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..324
		YRPW motif	314..317