Protein Alignment E(spl)m8-HLH and hes6

DIOPT Version :9

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_919381.2
• Gene: hes6 / 373116
• ZFINID: ZDB-GENE-030828-5
• Length: 226
• Species: Danio rerio
• Alignment Length: 218
• Identity: 57/218 - (26%)
• Similarity: 93/218 - (42%)
• Gaps: 60/218 - (27%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAV-----IFMRQQKTPKK 70
            :|.:||::|::||||:|:.|..|:.|:|:   .|..::|:.||:||..|     |...:.|....
Zfish    20 RKTRKPLVEKKRRARINESLQELRLLLAD---PDAQVKMENAEVLEMTVKRVESILQNKAKEADS 81

  Fly    71 VAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRV--YKNLQQFHEAQSAA 133
            |.:|..    :.|..||:..::||...::|.||:...:...::.||...  ..:.::|.:..|
Zfish    82 VNREAN----ERFAAGYIQCMHEVHTFVSSCPGIDATIAADLLNHLLECMPLNDEERFQDILS-- 140

  Fly   134 DFIQNSMDCSSMD----KAPLSP-----ASSGYHSDCDSPAPSPQPM------------------ 171
            |.|.:|.:..:..    .|.|||     |:.|  |...|||||....
Zfish   141 DLISDSNNSGTWPGEAAYATLSPGGTSVANGG--SSALSPAPSTTSSDDICSDLDDTDTEHSRIS 203

  Fly   172 -----QQP----------LWRPW 179
                 |.|          :||||
Zfish   204 VDAGDQAPVVPTLYTNKSIWRPW 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	21/60 (35%)
		ORANGE	81..125	CDD:128787	10/45 (22%)
hes6	NP_919381.2	HLH	18..75	CDD:238036	21/57 (37%)
		Hairy_orange	90..128	CDD:284859	10/37 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5073
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.750