DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E(spl)m8-HLH and Hesr

DIOPT Version :9

Sequence 1:	NP_524513.1	Gene:	E(spl)m8-HLH / 43161	FlyBaseID:	FBgn0000591	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_525094.1	Gene:	Hesr / 32800	FlyBaseID:	FBgn0030899	Length:	149	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	47/185 - (25%)
Similarity:	79/185 - (42%)	Gaps:	61/185 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDG--ILRMDKAEMLESAVIFMRQQKT 67
            :::..|::|.|||:||:||:|:|:|||.:|.|:.|:...||  :.:||..::||.||..:.::..
  Fly    16 SRSHQYREVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAVHHLSKKNC 80

  Fly    68 PKKVAQEE--------QSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQ 124
            |  ||...        || |:|.:.:|:...|.|||:.:
  Fly    81 P--VATPTTAPTSGVYQS-PIDCYWSGFRECVLEVSQFL-------------------------- 116

  Fly   125 QFHEAQSAADFIQNSMDCSSMDKAPLSPASSGYHSDCDSPAPSPQPMQQPLWRPW 179
            |.:..|.:.:|.:                      :.|....|....:..|||||
  Fly   117 QHNGYQPSFEFAK----------------------ELDHLVASTSKSKPNLWRPW 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	25/58 (43%)
E(spl)m8-HLH	NP_524513.1	ORANGE	81..125	CDD:128787	6/43 (14%)
Hesr	NP_525094.1	HLH	21..77	CDD:238036	25/55 (45%)
Hesr	NP_525094.1	Hairy_orange	101..>116	CDD:295407	5/14 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469373
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850