Protein Alignment E(spl)m8-HLH and Hes6

DIOPT Version :9

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001013197.1
• Gene: Hes6 / 316626
• RGDID: 1312047
• Length: 234
• Species: Rattus norvegicus
• Alignment Length: 209
• Identity: 52/209 - (24%)
• Similarity: 89/209 - (42%)
• Gaps: 48/209 - (22%)

  Fly    10 YQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAVIFMRQQKTPKKVAQE 74
            :.:.:||::|::||||:|:.|..|:.|:|   |.:...:::.||:||..|  .|.|...:..|:|
  Rat    35 FPQARKPLVEKKRRARINESLQELRLLLA---GTEVQAKLENAEVLELTV--RRVQGALRGRARE 94

  Fly    75 EQSLPLDS---FKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFI 136
            .:.|..::   |..||:..::||...:::...:...:...::.||    .......|..|..|.:
  Rat    95 REQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLNHL----LESMPLREGSSFRDLL 155

  Fly   137 QNSM-------DCSSMDK--APLSPASS--GYHSDCDS-------------PAPSPQPM------ 171
            .:|:       ..||...  :|.||.||  |...|..|             ||..|..:
  Rat   156 GDSLAGLPGGSGRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVPTSLGI 220

  Fly   172 ------QQPLWRPW 179
                  .|.:||||
  Rat   221 LTTARRAQSVWRPW 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	20/56 (36%)
		ORANGE	81..125	CDD:128787	7/46 (15%)
Hes6	NP_001013197.1	HLH	37..85	CDD:238036	19/52 (37%)
		Hairy_orange	106..144	CDD:284859	7/41 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	51	1.000	Inparanoid score	I5369
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.750