Protein Alignment E(spl)m8-HLH and Heyl

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_001101447.1
• Gene: Heyl / 313575
• RGDID: 1305022
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 174
• Identity: 33/174 - (18%)
• Similarity: 67/174 - (38%)
• Gaps: 45/174 - (25%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAVIFMRQQKTPKKVA-QE 74
            :|.::.::|::||.|:|..|..|:.||.......|..:::|||:|:..|..::......... .:
  Rat    44 RKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHASGGAGFFD 108

  Fly    75 EQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLG----RVYKNLQQFHEAQSAADF 135
            .::|.:|....|:...:.||.|.:....|.|        :|..    |:..:|..:
  Rat   109 ARALAVDFRSIGFRECLTEVVRYLGVLEGPS--------SHADPVRIRLLSHLNSY--------- 156

  Fly   136 IQNSMDCSSMDKAPLSPASSGYHSDCDSPAPSPQPMQQPLWRPW 179
                  .:.|:.:|.:..:..:                |:| ||
  Rat   157 ------AAEMEPSPTTTGALAF----------------PVW-PW 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	16/57 (28%)
		ORANGE	81..125	CDD:128787	10/47 (21%)
Heyl	NP_001101447.1	bHLH-O_HEYL	36..109	CDD:381453	16/64 (25%)
		ORANGE	115..162	CDD:128787	11/69 (16%)