Protein Alignment E(spl)m8-HLH and her3

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_571155.1
• Gene: her3 / 30289
• ZFINID: ZDB-GENE-980526-204
• Length: 229
• Species: Danio rerio
• Alignment Length: 225
• Identity: 55/225 - (24%)
• Similarity: 94/225 - (41%)
• Gaps: 54/225 - (24%)

  Fly     4 TTKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGI--LRMDKAEMLESAVIFMRQ-Q 65
            |.|.|..:||.||::|::||||:||||:.||:|: |....:.|  .:::||::||..|..:|. |
Zfish    10 TAKPQNVKKVSKPLMEKKRRARINKCLNQLKSLL-ESACSNNIRKRKLEKADILELTVKHLRHLQ 73

  Fly    66 KTPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHL--GRVYKNLQQF-- 126
            .|.:.:::...|.   .:..||.:.:|.||..:.:: ....|....::|:|  |..:..:..|
Zfish    74 NTKRGLSKACDSA---EYHAGYRSCLNTVSHYLRAS-DTDRDSRSIMLTNLTSGLNHNRVPDFST 134

  Fly   127 ------------------HEAQSAADFIQNSMDCSSMDKAPLSPASSGY-HSD---CDSPAPSPQ 169
                              |:.....|...:|...::..|..|.|..:.. .||   .|:...|.:
Zfish   135 VESDPALIFTLPSTLRRPHKVPIRTDVSYSSFQQTAERKVCLMPKRTEIGDSDRMSLDAALRSQE 199

  Fly   170 P--------------------MQQPLWRPW 179
            .                    .:|..||||
Zfish   200 SKKAETTHFRPKDLKVIECCIFKQNYWRPW 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	26/60 (43%)
		ORANGE	81..125	CDD:128787	9/45 (20%)
her3	NP_571155.1	bHLH_SF	24..78	CDD:469605	22/54 (41%)
		ORANGE	88..129	CDD:128787	9/41 (22%)