Protein Alignment E(spl)m8-HLH and her6

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_571154.2
• Gene: her6 / 30288
• ZFINID: ZDB-GENE-980526-144
• Length: 270
• Species: Danio rerio
• Alignment Length: 237
• Identity: 49/237 - (20%)
• Similarity: 94/237 - (39%)
• Gaps: 67/237 - (28%)

  Fly    10 YQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGI--LRMDKAEMLESAVIFMR-QQKTPKKV 71
            ::|..||::|::||||:|:.|..||||:.:....|..  .:::||::||..|..:| .|:.....
Zfish    34 HRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNMQRAQMTA 98

  Fly    72 AQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQ------------ 124
            |.......|..::.|:...:|||:|.:::..|::.::...::.||......:.
Zfish    99 ALNTDPTVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLASCMTQINAMNYPTQHQIPA 163

  Fly   125 ------------QFHEAQSAADFIQ-NSMDCSSMDKAPLS-------------PASSG------- 156
                        |...|...|:.:. :.:.|.|...:.|:             ||:.|
Zfish   164 GPPHPSFSQPMVQIPSATQQANVVPLSGVPCKSGSSSNLTSDATKVYGGFQLVPATDGQFAFLIP 228

  Fly   157 -------------YHSDCDSPAP------SPQPMQQPLWRPW 179
                         |.::.::|.|      :|......:||||
Zfish   229 NAAFAPNGPVIPVYANNSNTPVPVAVSPGAPSVTSDSVWRPW 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	22/60 (37%)
		ORANGE	81..125	CDD:128787	8/67 (12%)
her6	NP_571154.2	bHLH-O_HES1_4	33..95	CDD:381465	22/60 (37%)
		Hairy_orange	109..148	CDD:462193	8/38 (21%)