Protein Alignment E(spl)m8-HLH and Hes2

DIOPT Version :9

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: NP_062109.1
• Gene: Hes2 / 29567
• RGDID: 62082
• Length: 157
• Species: Rattus norvegicus
• Alignment Length: 177
• Identity: 60/177 - (33%)
• Similarity: 90/177 - (50%)
• Gaps: 41/177 - (23%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDD--GILRMDKAEMLESAVIFMRQQKTPKKVAQ 73
            :|..||:||::||||:|:.|..||.||..|.|.:  ...:::||::||..|.|:|:|  |..|..
  Rat    14 RKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQ--PASVCS 76

  Fly    74 EEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFIQN 138
            .|....|||:..||...:..::||:   |..|| |..:|.   .|:.::|:|
  Rat    77 TEAPGSLDSYLEGYRACLARLARVL---PACSV-LEPAVS---ARLLEHLRQ------------- 121

  Fly   139 SMDCSSMDKAP--LSPASSGYHSDCDSPAPSPQPMQQP----LWRPW 179
                .::...|  |:|||:      .:||||| |:..|    |||||
  Rat   122 ----RTVSGGPPSLTPASA------SAPAPSP-PVPPPSSLGLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	25/57 (44%)
		ORANGE	81..125	CDD:128787	13/43 (30%)
Hes2	NP_062109.1	HLH	12..69	CDD:238036	23/54 (43%)
		ORANGE	84..128	CDD:128787	14/67 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		15/39 (38%)
		WRPW motif	154..157		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47782
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850