| Sequence 1: | NP_524513.1 | Gene: | E(spl)m8-HLH / 43161 | FlyBaseID: | FBgn0000591 | Length: | 179 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_035628.1 | Gene: | Bhlhe40 / 20893 | MGIID: | 1097714 | Length: | 411 | Species: | Mus musculus |
| Alignment Length: | 223 | Identity: | 48/223 - (21%) |
|---|---|---|---|
| Similarity: | 81/223 - (36%) | Gaps: | 67/223 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MEYTTKTQIYQ---------------KVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMD 50
Fly 51 KAEMLESAVIFMRQQKTPKKVA-----QEEQSLPLDS------------------FKNGYMNAVN 92
Fly 93 EVSRVMASTPGMSVDLGKS-VMTHLGRVYKNLQQFHEAQSAADFIQNSMDCSSMDK--------- 147
Fly 148 ------------APLSPASSGYHSDCDS 163 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| E(spl)m8-HLH | NP_524513.1 | HLH | 10..67 | CDD:238036 | 17/71 (24%) |
| ORANGE | 81..125 | CDD:128787 | 15/62 (24%) | ||
| Bhlhe40 | NP_035628.1 | Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer. /evidence=ECO:0000250 | 1..139 | 24/116 (21%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..20 | ||||
| bHLH-O_DEC1 | 40..129 | CDD:381592 | 21/94 (22%) | ||
| Necessary for interaction with RXRA and repressor activity against RXRA. /evidence=ECO:0000250 | 75..79 | 2/3 (67%) | |||
| ORANGE | 140..184 | CDD:128787 | 14/44 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 207..294 | 7/37 (19%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167830899 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4304 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR10985 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.840 | |||||