Protein Alignment E(spl)m8-HLH and Hes5

DIOPT Version :9

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_006538625.3
• Gene: Hes5 / 15208
• MGIID: 104876
• Length: 415
• Species: Mus musculus
• Alignment Length: 200
• Identity: 50/200 - (25%)
• Similarity: 82/200 - (41%)
• Gaps: 52/200 - (26%)

  Fly    12 KVKKPMLERQRRARMNKCLDNLKTLV-AELRGDDGILRMDKAEMLESAVIFMRQQK--------- 66
            :::||::|:.||.|:|..::.||.|: .|........:::||::||.||.:::..|
Mouse   236 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKGEPGACARL 300

  Fly    67 -TPKKVAQEEQS--LPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHE 128
             .|..||...::  :|| .....:..|....|.....:.|.|..|.::|            ||..
Mouse   301 LLPADVAPTARAPLMPL-RLPTAFAAAAGPKSLHQDYSEGYSWCLQEAV------------QFLT 352

  Fly   129 AQSAADFIQNSMDCSSMDKAPLSPASSGYHSDCDSPAP--SPQP--------------MQQP--- 174
            ..:|:|.....:.......||.:||.       :.|||  :|||              .:||
Mouse   353 LHAASDTQMKLLYHFQRPPAPAAPAK-------EPPAPGAAPQPARSSAKAAAAAVSTSRQPACG 410

  Fly   175 LWRPW 179
            |||||
Mouse   411 LWRPW 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	HLH	10..67	CDD:238036	18/65 (28%)
		ORANGE	81..125	CDD:128787	6/43 (14%)
Hes5	XP_006538625.3	bHLH-O_HES5	236..292	CDD:381467	17/55 (31%)
		ORANGE	334..369	CDD:128787	8/46 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840