Protein Alignment E(spl)m8-HLH and hes7.2

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_002942675.1
• Gene: hes7.2 / 100496131
• XenbaseID: XB-GENE-486482
• Length: 243
• Species: Xenopus tropicalis
• Alignment Length: 221
• Identity: 50/221 - (22%)
• Similarity: 95/221 - (42%)
• Gaps: 55/221 - (24%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGIL--RMDKAEMLESAVIFMRQQKTPKKVAQ 73
            :::.||::|::||.|:|:.|::|:||:.|...|:.:.  :.:||::|:..|.|::....|  |..
 Frog    25 KRLMKPVIEKRRRDRINQSLEHLRTLLLEATHDETLKNPKAEKADILKKTVHFLKMCHNP--VPS 87

  Fly    74 EEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADF--- 135
            :.:.| |..||.|:...:|:.:..:.|...:.....:.|:..|.:..:...|.|...||.|.
 Frog    88 DGKKL-LSGFKGGFREGLNQATSFLNSADSICQKKKEYVVQRLCQHMEQQTQKHCHDSAQDVSSR 151

  Fly   136 -----------IQNSMDCSSMDKAPLSPASSGYHSDCDSPAPS--------------PQ------ 169
                       :.:.:..:.::::|.:..|...||...||:.|              ||
 Frog   152 VNQRQILPSPPLISRVTGNGLEQSPETQTSRPPHSHHPSPSSSFRTPCMGQEQQQTPPQTFQANT 216

  Fly   170 ---PMQQPL-------------WRPW 179
               |.|:.|             ||||
 Frog   217 NKKPTQRTLFPPTSSSVNSALVWRPW 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	19/59 (32%)
		ORANGE	81..125	CDD:128787	7/43 (16%)
hes7.2	XP_002942675.1	bHLH-O_HES7	25..79	CDD:381468	18/53 (34%)
		ORANGE	94..138	CDD:128787	7/43 (16%)