Protein Alignment E(spl)m8-HLH and hes6

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_017949954.1
• Gene: hes6 / 100126814
• XenbaseID: XB-GENE-1018104
• Length: 195
• Species: Xenopus tropicalis
• Alignment Length: 193
• Identity: 47/193 - (24%)
• Similarity: 85/193 - (44%)
• Gaps: 39/193 - (20%)

  Fly    13 VKKPMLERQRRARMNKCLDNLKTLVAELRGDDGILRMDKAEMLESAV----IFMRQQKTPKKVAQ 73
            ::||::|::||||:|:.|.:|:.::::.....   :|:.||:||..|    ..:|.:.......|
 Frog    16 MRKPLVEKRRRARINESLQDLRGILSDTEFQS---KMENAEVLELTVKRVERILRNRTAEADRLQ 77

  Fly    74 EEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQ-SAADFIQ 137
            .|.|   :.|..||:..::||...::|.||:...|...::.||      |:....:: |..|.:.
 Frog    78 REAS---ERFAAGYIQCMHEVHTFVSSCPGIDASLAAELLNHL------LESMPLSEGSLQDLVM 133

  Fly   138 NSM---------------------DCSSMDKAPLSPASSGYHSDCDSPAPSPQPMQQPLWRPW 179
            :.:                     .||.|:::....|..|...| ....|..||....:||||
 Frog   134 DVLLDSTSSEEGCGLGVLGSSSEDSCSDMEESEGEKAGMGSVQD-SGRTPEIQPPTPTMWRPW 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	17/60 (28%)
		ORANGE	81..125	CDD:128787	12/43 (28%)
hes6	XP_017949954.1	bHLH_SF	16..69	CDD:469605	17/55 (31%)
		Hairy_orange	83..122	CDD:462193	12/44 (27%)