Protein Alignment E(spl)m8-HLH and hes2

DIOPT Version :10

• Sequence 1: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Sequence 2: XP_002933889.1
• Gene: hes2 / 100038090
• XenbaseID: XB-GENE-486138
• Length: 191
• Species: Xenopus tropicalis
• Alignment Length: 187
• Identity: 52/187 - (27%)
• Similarity: 82/187 - (43%)
• Gaps: 42/187 - (22%)

  Fly    11 QKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDG--ILRMDKAEMLESAVIFMRQQKTPKKVAQ 73
            :|..||::|::||||:|:.|:.||||:..|.|.|.  ..:::||::||..|.|:|.  .|...||
 Frog    29 RKTLKPLMEKRRRARINESLNQLKTLILPLIGKDNSRYSKLEKADILEMTVRFLRD--IPPVPAQ 91

  Fly    74 EEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEAQSAADFIQN 138
            .    |.|.:|.||...|..:|.::..:..::.:....::.||.|                  ..
 Frog    92 N----PADRYKEGYRACVERLSAILNKSHVLTGEASNRLLNHLQR------------------SP 134

  Fly   139 SMDCSSMDKAP----------LSPASSGYHS------DCDSPAPSPQPMQQPLWRPW 179
            .:.||.....|          :||.:|...|      ....|||.|..:...:||||
 Frog   135 ELCCSDCHHPPKSHSPRIVLHVSPRTSQLESPLLNQPSSHRPAPCPPQLNSSIWRPW 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	25/59 (42%)
		ORANGE	81..125	CDD:128787	9/43 (21%)
hes2	XP_002933889.1	bHLH-O_HES2	25..89	CDD:381469	25/61 (41%)
		Hairy_orange	96..133	CDD:462193	8/54 (15%)