Protein Alignment E(spl)m7-HLH and Hes7

DIOPT Version :9

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_149030.2
• Gene: Hes7 / 84653
• MGIID: 2135679
• Length: 225
• Species: Mus musculus
• Alignment Length: 231
• Identity: 63/231 - (27%)
• Similarity: 93/231 - (40%)
• Gaps: 52/231 - (22%)

  Fly     1 MATKYEMSKTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD-----AKFEKADILEV 60
            |.|: |.::.....|::|||:|::||.|||:.|:||:.|:.|   :|.|     .|.|||:|||.
Mouse     1 MVTR-ERAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLE---RTRDQNLRNPKLEKAEILEF 61

  Fly    61 TVQHLR-KLKESKKHVPANPEQSFRA---GYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLN 121
            .|.:|| :.:.....||.:|.|...|   .|:....|....||:... |.:  ....:.|...|:
Mouse    62 AVGYLRERSRVEPPGVPRSPGQDAEALASCYLSGFRECLLRLAAFAH-DAS--PAARSQLFSALH 123

  Fly   122 QLEQPM-EQPQAVN----------TPLSIVCGSS-----------SSSSTYSSASSCSS------ 158
            ...:|. .:|:||:          .|.|.:.|.:           .|.....|.|.|||
Mouse   124 GYRRPKPPRPEAVDPGLPAPRPPLDPASPILGPALHQRPPVHQGPPSPRLAWSPSHCSSRAGDSG 188

  Fly   159 --------ISPVSSGYASDNESLLQISSPGQVWRPW 186
                    :.|....|..|.........|...||||
Mouse   189 APAPLTGLLPPPPPPYRQDGAPKAPSLPPPAFWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	HLH	13..73	CDD:238036	27/65 (42%)
		ORANGE	81..125	CDD:128787	9/46 (20%)
Hes7	NP_149030.2	HLH	14..73	CDD:238036	27/61 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..225		21/101 (21%)
		WRPW motif	221..224		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740