DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)m7-HLH and Bhlhe41

DIOPT Version :9

Sequence 1:NP_536753.1 Gene:E(spl)m7-HLH / 43160 FlyBaseID:FBgn0002633 Length:186 Species:Drosophila melanogaster
Sequence 2:NP_077789.1 Gene:Bhlhe41 / 79362 MGIID:1930704 Length:410 Species:Mus musculus


Alignment Length:205 Identity:57/205 - (27%)
Similarity:87/205 - (42%) Gaps:58/205 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 TYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGDAKFEKADILEVTVQHLRKL-----K 69
            ||   |:...|:|:|||.|||:|:.:||||:.|.:..|.....|||.:||:|::||:.|     :
Mouse    44 TY---KLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKALTALTEQ 105

  Fly    70 ESKKHVP-ANPEQS-----------FRAGYIRAANEVSRALASL-------PRVDVAFGTTLMTH 115
            :.:|.:. .|.|:|           |.:|:...|.||.:.||..       ||.     ..|::|
Mouse   106 QHQKIIALQNGERSLKSPVQADLDAFHSGFQTCAKEVLQYLARFESWTPREPRC-----AQLVSH 165

  Fly   116 LGMRLNQLEQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSIS---PV--------------- 162
            |.....||..|       ..|.....|.:..|:..::||....::   ||               
Mouse   166 LHAVATQLLTP-------QVPSGRGSGRAPCSAGAAAASGPERVARCVPVIQRTQPGTEPEHDTD 223

  Fly   163 -SSGYASDNE 171
             .|||..:.|
Mouse   224 TDSGYGGEAE 233

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)m7-HLHNP_536753.1 HLH 13..73 CDD:238036 25/64 (39%)
ORANGE 81..125 CDD:128787 15/61 (25%)
Bhlhe41NP_077789.1 bHLH-O_DEC2 31..122 CDD:381593 31/80 (39%)
ORANGE 129..175 CDD:128787 14/50 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 209..255 4/25 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 360..410
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830862
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.840

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