Protein Alignment E(spl)m7-HLH and bhlhe40

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: XP_004914192.2
• Gene: bhlhe40 / 779502
• XenbaseID: XB-GENE-486416
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 202
• Identity: 52/202 - (25%)
• Similarity: 93/202 - (46%)
• Gaps: 50/202 - (24%)

  Fly     7 MSKTYQYRKVMK--------------PLLERKRRARINKCLDELKDLMAECVAQTGDAKFEKADI 57
            |...:::||.:|              .|:|:|||.|||:|:.:||||:.|.:..|.....|||.:
 Frog    54 MYPVFKHRKALKRCEESKQDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVV 118

  Fly    58 LEVTVQHLRKL----KESKKHV-------PA-----NPEQSFRAGYIRAANEVSRALASLPRVDV 106
            ||:|::|:|.|    ::.::.:       |:     :.|:.|.:|:...|.|..|.|....|.:
 Frog   119 LELTLKHVRSLSSLIEQQQQQILTLQSGSPSEENRISAEEMFHSGFQLCAEEALRFLQGGERKE- 182

  Fly   107 AFGTTLMTHLGMRLNQL---------EQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSISPV 162
                 |:.||....::|         |:|:.:.||.|. :.::|.::...|...|.:.    :..
 Frog   183 -----LVAHLHRVASKLGPASFPKVTEKPVPKVQATNC-VPVICRAAPLPSGEQSGTD----TDT 237

  Fly   163 SSGYASD 169
            .|||..:
 Frog   238 DSGYGGE 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	28/83 (34%)
		ORANGE	81..125	CDD:128787	11/52 (21%)
bhlhe40	XP_004914192.2	bHLH_SF	61..151	CDD:469605	28/89 (31%)
		Hairy_orange	159..192	CDD:462193	10/38 (26%)