Protein Alignment E(spl)m7-HLH and hes5.2

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_001037974.1
• Gene: hes5.2 / 733755
• XenbaseID: XB-GENE-876635
• Length: 158
• Species: Xenopus tropicalis
• Alignment Length: 179
• Identity: 51/179 - (28%)
• Similarity: 82/179 - (45%)
• Gaps: 47/179 - (26%)

  Fly    15 KVMKPLLERKRRARINKCLDELKDLMAECV--AQTGDAKFEKADILEVTVQHLR-KLKESKKHVP 76
            |:.||::|:.||.|||..:::||.|: |.|  .|..:.|.|||||||:||.:|| :..:.|..:|
 Frog    20 KLRKPVVEKMRRDRINSSIEQLKGLL-ETVFHKQQPNVKLEKADILEMTVTYLRQQTLQIKSEIP 83

  Fly    77 ANP--EQSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLEQPMEQPQAVNTPLSI 139
            .|.  :..::.||.|...||                         ::.|....:||:
 Frog    84 HNNDIQMDYKDGYSRCFEEV-------------------------IDFLSLHQKQPE-------- 115

  Fly   140 VCGSSSSSSTYSSASSCSSIS--PVSSGYASDNESLLQISSPGQVWRPW 186
               ::...|.:.|.::.||||  |:.   .|.:::.....|...:||||
 Frog   116 ---TAKLISHFHSKATASSISSFPIR---CSQSKTANGTGSSSSLWRPW 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	27/60 (45%)
		ORANGE	81..125	CDD:128787	6/43 (14%)
hes5.2	NP_001037974.1	bHLH-O_HES5	20..77	CDD:381467	27/57 (47%)
		ORANGE	90..128	CDD:128787	10/73 (14%)