Protein Alignment E(spl)m7-HLH and Hes3

DIOPT Version :9

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_073178.1
• Gene: Hes3 / 64628
• RGDID: 621339
• Length: 175
• Species: Rattus norvegicus
• Alignment Length: 205
• Identity: 56/205 - (27%)
• Similarity: 87/205 - (42%)
• Gaps: 69/205 - (33%)

  Fly    21 LERKRRARINKCLDELKDLMAECVA-QTGDAKFEKADILEVTVQHLRKLKESKKH---VPANPE- 80
            :|:|||||||..|::|:.|:....: |....|.|||||||::|:::|.|:.|.:.   ||:..:
  Rat     1 MEKKRRARINLSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQGLWLVPSGVDY 65

  Fly    81 -QSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLEQPMEQPQAVNTPLSIV--CG 142
             ..||.|              ||      |:          :|..:|.|....:..||.:.  .|
  Rat    66 PSGFRGG--------------LP------GS----------SQRLRPGEDDSGLRCPLLLQRRAG 100

  Fly   143 SSSSSSTYSSASSCSSISPV------SSGYASDNES-------LLQISS---------------- 178
            |::.|:...:||..|...|.      .:|.:...:|       ||:.|:
  Rat   101 STTDSANPQTASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENP 165

  Fly   179 -PG-QVWRPW 186
             || :|||||
  Rat   166 RPGFRVWRPW 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	HLH	13..73	CDD:238036	24/52 (46%)
		ORANGE	81..125	CDD:128787	7/43 (16%)
Hes3	NP_073178.1	bHLH-O_HES3	1..55	CDD:381503	24/53 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..175		10/50 (20%)
		WRPW motif	172..175		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840