Protein Alignment E(spl)m7-HLH and hey1

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_997726.2
• Gene: hey1 / 58008
• ZFINID: ZDB-GENE-000607-70
• Length: 318
• Species: Danio rerio
• Alignment Length: 209
• Identity: 60/209 - (28%)
• Similarity: 90/209 - (43%)
• Gaps: 52/209 - (24%)

  Fly    12 QYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGDAKFEKADILEVTVQHLRKLKES--KKH 74
            |.||..:.::|::||.|||..|.||:.|:.....:.|.||.|||:||::||.||:.|..:  |.:
Zfish    47 QARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHAAGGKGY 111

  Fly    75 VPANP-EQSFRA-GYIRAANEVSRALASLPRVD-------------------------------- 105
            ..|:. ...:|. |:.....|.:|.|:.:..:|
Zfish   112 FDAHALAMDYRGLGFRECLAETARYLSIIEGLDNTDPLRIRLVSHLNSYASQREAHSGLGHLAWG 176

  Fly   106 VAFGTT---LMTHLGMRLNQLEQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSISPVSSGYA 167
            .||||.   |..||.::..|.:|.....::.::|     .||:|||..||:.|..|..|..||..
Zfish   177 SAFGTPPSHLAHHLLLQQQQQQQGAPLARSTSSP-----PSSNSSSPSSSSPSAPSTEPRLSGTV 236

  Fly   168 SDNESLLQISSPGQ 181
                    ||..||
Zfish   237 --------ISEAGQ 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	26/62 (42%)
		ORANGE	81..125	CDD:128787	14/79 (18%)
hey1	NP_997726.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		4/11 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..265		19/62 (31%)
		YRPW motif	308..311