Protein Alignment E(spl)m7-HLH and hes1

DIOPT Version :9

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_001011194.1
• Gene: hes1 / 496617
• XenbaseID: XB-GENE-487995
• Length: 267
• Species: Xenopus tropicalis
• Alignment Length: 255
• Identity: 70/255 - (27%)
• Similarity: 108/255 - (42%)
• Gaps: 73/255 - (28%)

  Fly     2 ATKYEMSKT-------YQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD--AKFEKADI 57
            ||...||.|       .::||..||::|::||||||:.|.:||.|:.:.:.:...  :|.|||||
 Frog    16 ATPASMSNTPDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADI 80

  Fly    58 LEVTVQHLRKLKESKKHVPANPEQS----FRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGM 118
            ||:||:|||.|:..:.....:.:.|    :|||:....|||:|.|::...|:....|.|:.||..
 Frog    81 LEMTVKHLRNLQRVQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTDVRTRLLGHLAN 145

  Fly   119 RLNQLE---------------------QPMEQPQAV---NTPLSIVC------------------ 141
            .:||:.                     ||:.|.|..   ::|..|.|
 Frog   146 CMNQINAMNYPTQPQIPAAAAPHPAYGQPLVQLQGAAPQSSPAPIACKMGGPPVEAAKVYGGFQL 210

  Fly   142 -----GSSSSSSTYSSASSCSSISPVSSGYASDN----------ESLLQISSPGQVWRPW 186
                 |..:...|..:.....|:.||   |.:.|          .|::...:...|||||
 Frog   211 VPAPDGQFAFLITNPAFPHNGSVIPV---YTNSNVGTALPPSVSPSVMPSVTADSVWRPW 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	HLH	13..73	CDD:238036	29/61 (48%)
		ORANGE	81..125	CDD:128787	16/68 (24%)
hes1	NP_001011194.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		10/28 (36%)
		bHLH-O_HES1_4	33..95	CDD:381465	29/61 (48%)
		Hairy_orange	110..148	CDD:369405	13/37 (35%)
		WRPW motif. /evidence=ECO:0000255	264..267		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010