Protein Alignment E(spl)m7-HLH and E(spl)m3-HLH

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 86/228 - (37%)
• Similarity: 119/228 - (52%)
• Gaps: 54/228 - (23%)

  Fly     6 EMSKTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD--AKFEKADILEVTVQHLRKL 68
            |||||||||||||||||||||||||||||:|||||.||:.|.|:  .:.|||||||:||.|:|||
  Fly     4 EMSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKL 68

  Fly    69 KE--------------------SKKHVPANPEQSFRAGYIRAANEVSRALASLPRVD------VA 107
            |:                    |..||     :|||:||:.||:::::.|....:.|      :.
  Fly    69 KQRGGLSLQGVVAGVGSPPTSTSTAHV-----ESFRSGYVHAADQITQVLLQTQQTDEIGRKIMK 128

  Fly   108 FGTTLMTHLGMRLNQLEQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSISPVSSGYASDNES 172
            |.:|.:..|..:|.|.:|..:|.|....|.|....:......|..|::.::||  .|.:.:..:.
  Fly   129 FLSTRLIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAIS--YSSFLTSKDE 191

  Fly   173 LLQISS-------------------PGQVWRPW 186
            |:.::|                   ...|||||
  Fly   192 LIDVTSVDGNALSETASVSSQESGASEPVWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	52/87 (60%)
		ORANGE	81..125	CDD:128787	14/49 (29%)
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	51/65 (78%)
		ORANGE	96..136	CDD:128787	11/39 (28%)