DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment E(spl)m7-HLH and dpn

DIOPT Version :9

Sequence 1:	NP_536753.1	Gene:	E(spl)m7-HLH / 43160	FlyBaseID:	FBgn0002633	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_476923.1	Gene:	dpn / 35800	FlyBaseID:	FBgn0010109	Length:	435	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	60/177 - (33%)
Similarity:	93/177 - (52%)	Gaps:	25/177 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATKYEMSKTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQ--TGDAKFEKADILEVTVQ 63
            |:....:||. :.||..||::|::||||||.||:|||.|:.|.:.:  ....|.|||||||:||:
  Fly    29 MSNPNGLSKA-ELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVK 92

  Fly    64 HLRKLKESKKH--VPANPE--QSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLE 124
            ||:.::..:.:  :.::|.  |.|:.|::..|.||:|.::.:..:|......|..||....|.||
  Fly    93 HLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLE 157

  Fly   125 Q----------------PMEQPQAVNTPL--SIVCGSSSSSSTYSSA 153
            |                |.....|..|||  |:....:::|.|.|||
  Fly   158 QIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRTESSA 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	HLH	13..73	CDD:238036	30/61 (49%)
E(spl)m7-HLH	NP_536753.1	ORANGE	81..125	CDD:128787	13/43 (30%)
dpn	NP_476923.1	HLH	39..101	CDD:238036	30/61 (49%)
dpn	NP_476923.1	ORANGE	114..158	CDD:128787	13/43 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438362
Domainoid	1	1.000	45	1.000	Domainoid score	I4621
eggNOG	1	0.900	-	-		E1_KOG4304
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840