Protein Alignment E(spl)m7-HLH and her6

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_571154.2
• Gene: her6 / 30288
• ZFINID: ZDB-GENE-980526-144
• Length: 270
• Species: Danio rerio
• Alignment Length: 250
• Identity: 75/250 - (30%)
• Similarity: 118/250 - (47%)
• Gaps: 64/250 - (25%)

  Fly     1 MATKYEMSKT-YQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD--AKFEKADILEVTV 62
            |.|..:..|| .::||..||::|::||||||:.|.:||.|:.:.:.:...  :|.|||||||:||
Zfish    21 MNTTPDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTV 85

  Fly    63 QHLRKLKESKKHVPANPEQS----FRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQL 123
            :|||.::.::.....|.:.:    :|||:....|||:|.|::...|:....|.|:.||...:.|:
Zfish    86 KHLRNMQRAQMTAALNTDPTVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLASCMTQI 150

  Fly   124 --------------------EQPMEQ-----PQAVNTPLS-IVCGSSSSSSTYSSASSC---SSI 159
                                .|||.|     .||...||| :.|.|.|||:..|.|:..   ..:
Zfish   151 NAMNYPTQHQIPAGPPHPSFSQPMVQIPSATQQANVVPLSGVPCKSGSSSNLTSDATKVYGGFQL 215

  Fly   160 SPVSSG--------------------YASDNESLLQIS-SPG-------QVWRPW 186
            .|.:.|                    ||:::.:.:.:: |||       .|||||
Zfish   216 VPATDGQFAFLIPNAAFAPNGPVIPVYANNSNTPVPVAVSPGAPSVTSDSVWRPW 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	30/68 (44%)
		ORANGE	81..125	CDD:128787	14/67 (21%)
her6	NP_571154.2	bHLH-O_HES1_4	33..95	CDD:381465	28/61 (46%)
		Hairy_orange	109..148	CDD:462193	13/38 (34%)