Protein Alignment E(spl)m7-HLH and ref-1

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_496204.1
• Gene: ref-1 / 174585
• WormBaseID: WBGene00004334
• Length: 367
• Species: Caenorhabditis elegans
• Alignment Length: 223
• Identity: 48/223 - (21%)
• Similarity: 81/223 - (36%)
• Gaps: 69/223 - (30%)

  Fly    14 RKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD--AKFEKADILEVTVQHLRKLKESKKH-- 74
            ||.:|...|:.||.|..:..|.||:.:.|....|..  .|.::.:.|::.:.::    ::|||
 Worm   163 RKEVKKNREQDRRDRQGEAFDALKNFIIENKLMTSHQVEKMQRLNTLDIIIAYI----QNKKHNF 223

  Fly    75 -VPANPEQSFRAGYIRAANEVSRALA-SLPRVDVAFGTTLMTHLGMRLNQLEQ------------ 125
             ..::.|||..|..|....:.::.:| ...:.|        .||.:|...||:
 Worm   224 VSRSDQEQSLYAHAIAEGKKTAKNIAFQFFKSD--------RHLVVRCADLEKFFEFSLSPKPLF 280

  Fly   126 -------------------------PMEQPQAVNTPLSIVCGSSSSSSTY-------SSASSCSS 158
                                     ||.......:|      .|..|.:|       ||.:|.||
 Worm   281 GFPSMPIPIPPPSFPIFPFRPFPFFPMPMAPMATSP------KSQQSPSYSLDSPPPSSDTSSSS 339

  Fly   159 ISPVSSGYASDNESLLQISSPGQVWRPW 186
            |...|:...:.| |..:.|...:::|||
 Worm   340 IETPSTPNENSN-SNPKASRKSKLFRPW 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	14/60 (23%)
		ORANGE	81..125	CDD:128787	10/44 (23%)
ref-1	NP_496204.1	HLH	20..66	CDD:197674
		HLH	170..217	CDD:197674	11/50 (22%)