Protein Alignment E(spl)m7-HLH and Hey1

DIOPT Version :9

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_034553.2
• Gene: Hey1 / 15213
• MGIID: 1341800
• Length: 299
• Species: Mus musculus
• Alignment Length: 245
• Identity: 61/245 - (24%)
• Similarity: 100/245 - (40%)
• Gaps: 74/245 - (30%)

  Fly    14 RKVMKPLLERKRRARINKCLDELKDLMAECVAQTGDAKFEKADILEVTVQHLRKLKES--KKHVP 76
            ||..:.::|::||.|||..|.||:.|:.....:.|.||.|||:||::||.||:.|..:  |.:..
Mouse    50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFD 114

  Fly    77 ANP-EQSFRA-GYIRAANEVSRALASLPRVDVA--FGTTLMTHLGMRLNQLE------------- 124
            |:. ...:|: |:.....||:|.|:.:..:|.:  ....|::||....:|.|
Mouse   115 AHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHGGLGHIP 179

  Fly   125 ------------QPMEQPQ-----------------------------AVNTPLSIVCG------ 142
                        .|:..||                             |:..|.|...|
Mouse   180 WGSAFGHHPHIAHPLLLPQNGHGNAGTAASPTEPHHQGRLASAHPEAPALRAPPSGGLGPVLPVV 244

  Fly   143 SSSSSSTYSSASSCSSISPVSSGYASDNESLLQISSP------GQVWRPW 186
            :|:|..:....||.:|:|.....::|.:  ||..|:|      |:.:|||
Mouse   245 TSASKLSPPLLSSVASLSAFPFSFSSFH--LLSPSTPTQAANLGKPYRPW 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	HLH	13..73	CDD:238036	25/60 (42%)
		ORANGE	81..125	CDD:128787	12/71 (17%)
Hey1	NP_034553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		2/2 (100%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250	48..117		27/66 (41%)
		HLH	50..107	CDD:238036	25/56 (45%)
		ORANGE	120..166	CDD:128787	11/45 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..234		4/39 (10%)
		YRPW motif	289..292		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740