Protein Alignment E(spl)m7-HLH and Hes5

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: XP_006538625.3
• Gene: Hes5 / 15208
• MGIID: 104876
• Length: 415
• Species: Mus musculus
• Alignment Length: 205
• Identity: 49/205 - (23%)
• Similarity: 85/205 - (41%)
• Gaps: 40/205 - (19%)

  Fly     6 EMSKTYQYRKVMKPLLERKRRARINKCLDELKDLM-AECVAQTGDAKFEKADILEVTVQHLRKLK 69
            ||....:..::.||::|:.||.|||..:::||.|: .|......::|.|||||||:.|.:|:..|
Mouse   227 EMLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSK 291

  Fly    70 E-----SKKHVPANPEQSFRAGYIRAANEVSRALASLPR---VDVAFG-----------TTLM-- 113
            .     ::..:||:...:.||..:......:.|.|:.|:   .|.:.|           .||.
Mouse   292 GEPGACARLLLPADVAPTARAPLMPLRLPTAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAA 356

  Fly   114 --THLGMRLNQLEQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSISPVSSGYASDNESLLQI 176
              |.:.:..:....|.....|...|........:.||..::|::.|:....:.|
Mouse   357 SDTQMKLLYHFQRPPAPAAPAKEPPAPGAAPQPARSSAKAAAAAVSTSRQPACG----------- 410

  Fly   177 SSPGQVWRPW 186
                 :||||
Mouse   411 -----LWRPW 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	24/71 (34%)
		ORANGE	81..125	CDD:128787	10/61 (16%)
Hes5	XP_006538625.3	bHLH-O_HES5	236..292	CDD:381467	22/55 (40%)
		ORANGE	334..369	CDD:128787	5/34 (15%)