Protein Alignment E(spl)m7-HLH and Hes3

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: XP_011248491.1
• Gene: Hes3 / 15207
• MGIID: 104877
• Length: 291
• Species: Mus musculus
• Alignment Length: 193
• Identity: 58/193 - (30%)
• Similarity: 89/193 - (46%)
• Gaps: 35/193 - (18%)

  Fly    16 VMKPLLERKRRARINKCLDELKDLMAECVA-QTGDAKFEKADILEVTVQHLRKLKESKKHV-PAN 78
            :.|||:|:|||||||..|::|:.|:....: |....|.|||||||::|:::|.|:.|.:.: |..
Mouse   112 ISKPLMEKKRRARINVSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 176

  Fly    79 PEQSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLEQPME-------QPQAVN-- 134
            ....:.:|:......||:      |:....|.:     |:|...|.|..|       .|||.:
Mouse   177 SGVDYPSGFQGGLRGVSQ------RLRPGEGDS-----GLRCPLLLQRREGSTTDSANPQATSVL 230

  Fly   135 --------TPLSIVCGSSSSSSTYSSASSC--SSISPVSSGYASDNESLLQISSPG-QVWRPW 186
                    .|.....||.|..|........  ||...|:...||:.::  :.:.|| :|||||
Mouse   231 NPCLPAIWAPSRAAGGSHSPQSPLPLPGGLLESSTDVVAPHPASNCQA--ESTRPGFRVWRPW 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	27/57 (47%)
		ORANGE	81..125	CDD:128787	8/43 (19%)
Hes3	XP_011248491.1	bHLH-O_HES3	117..171	CDD:381503	24/53 (45%)