Protein Alignment E(spl)m7-HLH and Hes2

DIOPT Version :10

• Sequence 1: NP_536753.1
• Gene: E(spl)m7-HLH / 43160
• FlyBaseID: FBgn0002633
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_032262.2
• Gene: Hes2 / 15206
• MGIID: 1098624
• Length: 157
• Species: Mus musculus
• Alignment Length: 185
• Identity: 57/185 - (30%)
• Similarity: 81/185 - (43%)
• Gaps: 49/185 - (26%)

  Fly    12 QYRKVMKPLLERKRRARINKCLDELKDLMAECV-AQTG-DAKFEKADILEVTVQHLRK----LKE 70
            :.||.:|||||::||||||:.|.:||.|:...: |:|. .:|.|||||||:||:.|::    |..
Mouse    12 ELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATLYS 76

  Fly    71 SKKHVPANPEQSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLEQPMEQPQAVNT 135
            |....|.|   |:..||......::|.|.:...::.|....|:.||..|
Mouse    77 SAAPGPLN---SYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQR---------------- 122

  Fly   136 PLSIVCGSSSSSSTYSSASSCSSISPV----SSGYASDNESLLQISSPGQVWRPW 186
                .....|.|.|...|.:.:...||    |||                :||||
Mouse   123 ----TVSDDSPSLTLPPAPAPAPSPPVPPPGSSG----------------LWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m7-HLH	NP_536753.1	bHLH-O_ESMB_like	7..73	CDD:381584	32/66 (48%)
		ORANGE	81..125	CDD:128787	10/43 (23%)
Hes2	NP_032262.2	bHLH_SF	10..73	CDD:469605	30/60 (50%)
		ORANGE	85..123	CDD:128787	10/57 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		11/48 (23%)
		WRPW motif	154..157		2/2 (100%)