Protein Alignment E(spl)m5-HLH and Hes7

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_149030.2
• Gene: Hes7 / 84653
• MGIID: 2135679
• Length: 225
• Species: Mus musculus
• Alignment Length: 215
• Identity: 49/215 - (22%)
• Similarity: 82/215 - (38%)
• Gaps: 60/215 - (27%)

  Fly    20 KVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAIL--RMDKAEMLEAALVFMRK--QVVKQQAP 80
            |:.|||:|::||.|:|:.|:.|:.|:.|...|..:.  :::|||:||.|:.::|:  :|.....|
Mouse    14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVP 78

  Fly    81 VSP-LPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHL-----GVEFQRMLQADQVQTSV 139
            .|| ...::..:.|::...|....:|   |.:.|......:.|     |....:..:.:.|...:
Mouse    79 RSPGQDAEALASCYLSGFRECLLRLA---AFAHDASPAARSQLFSALHGYRRPKPPRPEAVDPGL 140

  Fly   140 TTSTPRPLSPAS------------------------SGYHSDNEDSQSAA----------SPKPV 170
            ....| ||.|||                        |..|..:....|.|          .|.|.
Mouse   141 PAPRP-PLDPASPILGPALHQRPPVHQGPPSPRLAWSPSHCSSRAGDSGAPAPLTGLLPPPPPPY 204

  Fly   171 EE------------TMWRPW 178
            .:            ..||||
Mouse   205 RQDGAPKAPSLPPPAFWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	22/61 (36%)
		ORANGE	87..131	CDD:128787	7/48 (15%)
Hes7	NP_149030.2	bHLH_SF	13..73	CDD:469605	21/58 (36%)
		PRK14954	<96..>189	CDD:184918	16/96 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..225		18/102 (18%)
		WRPW motif	221..224		2/2 (100%)