Protein Alignment E(spl)m5-HLH and bhlhe40

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: XP_004914192.2
• Gene: bhlhe40 / 779502
• XenbaseID: XB-GENE-486416
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 188
• Identity: 43/188 - (22%)
• Similarity: 71/188 - (37%)
• Gaps: 42/188 - (22%)

  Fly    13 SKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAILRMDKAEMLEAALVFMR---KQV 74
            ||...| |:...|:|::||.|:|:|:..||.|:.|......:..::||.:||..|..:|   ..:
 Frog    70 SKQDTY-KLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVRSLSSLI 133

  Fly    75 VKQQAPVSPLPMDS------------FKNGYMNAVSEISRVMACTPAMSVDVG---KTVMTHL-- 122
            .:||..:..|...|            |.:|:.....|..|.:.         |   |.::.||
 Frog   134 EQQQQQILTLQSGSPSEENRISAEEMFHSGFQLCAEEALRFLQ---------GGERKELVAHLHR 189

  Fly   123 ------GVEFQRMLQADQVQTSVTTSTP-----RPL-SPASSGYHSDNEDSQSAASPK 168
                  ...|.::.:....:...|...|     .|| |...||..:|.:......:.|
 Frog   190 VASKLGPASFPKVTEKPVPKVQATNCVPVICRAAPLPSGEQSGTDTDTDSGYGGEADK 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	18/60 (30%)
		ORANGE	87..131	CDD:128787	10/66 (15%)
bhlhe40	XP_004914192.2	bHLH_SF	61..151	CDD:469605	25/81 (31%)
		Hairy_orange	159..192	CDD:462193	8/41 (20%)