Protein Alignment E(spl)m5-HLH and hes7

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_001039166.1
• Gene: hes7 / 733997
• XenbaseID: XB-GENE-876465
• Length: 178
• Species: Xenopus tropicalis
• Alignment Length: 184
• Identity: 47/184 - (25%)
• Similarity: 84/184 - (45%)
• Gaps: 30/184 - (16%)

  Fly    12 VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAIL--RMDKAEMLEAALVFMR-KQ 73
            |...:.:.|:.|||:||:||.|:|..|:.|:..:::....:.:.  :::|||:||..:.|:: .:
 Frog     7 VRPMEAHRKLLKPLVERRRRERINNSLEKLRIFLSQALKSEKLKNPKVEKAEILECTVQFLQSSK 71

  Fly    74 VVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQVQTS 138
            :|.|...|.   ...:::|:.:.:......|...|.::| ..|..::|     |........:..
 Frog    72 LVPQDGDVG---NKGYQSGFQHCLETALHFMNSKPDLNV-ATKDFLSH-----QLSSYKPPAEAW 127

  Fly   139 VTTSTPRPLSPASSGYH------SDNEDSQSAA--------SPKPVEETMWRPW 178
            ..|.||:| :| |.||.      |.|..|.|..        ||:..:  .||||
 Frog   128 SPTDTPKP-TP-SIGYQDSAPHLSSNTISVSPTKTLVDGQFSPQTFQ--TWRPW 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	19/60 (32%)
		ORANGE	87..131	CDD:128787	7/43 (16%)
hes7	NP_001039166.1	bHLH-O_HES7	14..74	CDD:381468	18/59 (31%)
		Hairy_orange	84..121	CDD:462193	7/42 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..147		8/26 (31%)
		WRPW motif. /evidence=ECO:0000255	174..177		2/2 (100%)