DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment E(spl)m5-HLH and hes5.7

DIOPT Version :9

Sequence 1:NP_524511.1 Gene:E(spl)m5-HLH / 43158 FlyBaseID:FBgn0002631 Length:178 Species:Drosophila melanogaster
Sequence 2:NP_001037989.1 Gene:hes5.7 / 733782 XenbaseID:XB-GENE-5922592 Length:148 Species:Xenopus tropicalis


Alignment Length:183 Identity:48/183 - (26%)
Similarity:85/183 - (46%) Gaps:40/183 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAPQSNNSTTFVS---KTQHYLKVKKPLLERQRRARMNKCLDTLKTLV-AEFQGDDAILRMDKAE 61
            |||.|  :|..:|   |:|...|::||::|:.||.|:|..::.|:.|: .||:......:.:||:
 Frog     1 MAPYS--ATNILSTEHKSQGIRKMRKPVVEKMRRDRINSSIEQLRMLLEKEFEKHHLPSKPEKAD 63

  Fly    62 MLEAALVFMRKQVVKQQAPV-SPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVE 125
            :||.|:.|:::::..:.|.. ||:.|:.......:::.        .|..|              
 Frog    64 ILEVAVSFLQQRMATKYAQSDSPVHMEDHSRYLQDSLQ--------FPEFS-------------- 106

  Fly   126 FQRMLQADQVQTSVTTSTPRPLSPASSGYHSDNEDSQSAASPKPVEETMWRPW 178
             ::.|.:.....|||.|.  ||||.   |.:..:.....||     :.:||||
 Frog   107 -KKFLHSFHEDHSVTVSP--PLSPL---YQTPTKCKTPWAS-----KVLWRPW 148

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)m5-HLHNP_524511.1 HLH 20..72 CDD:238036 18/52 (35%)
ORANGE 87..131 CDD:128787 2/43 (5%)
hes5.7NP_001037989.1 bHLH-O_HES5 21..75 CDD:381467 18/53 (34%)
EEP <87..145 CDD:382041 15/90 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 65 1.000 Inparanoid score I5183
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1378299at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.970

Return to query results.
Submit another query.