DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)m5-HLH and hes5.2

DIOPT Version :9

Sequence 1:NP_524511.1 Gene:E(spl)m5-HLH / 43158 FlyBaseID:FBgn0002631 Length:178 Species:Drosophila melanogaster
Sequence 2:NP_001037974.1 Gene:hes5.2 / 733755 XenbaseID:XB-GENE-876635 Length:158 Species:Xenopus tropicalis


Alignment Length:187 Identity:48/187 - (25%)
Similarity:86/187 - (45%) Gaps:38/187 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAPQSNNSTTFVSK----TQHYLKVKKPLLERQRRARMNKCLDTLKTLV-AEFQGDDAILRMDKA 60
            |||    ||.|:.:    .:...|::||::|:.||.|:|..::.||.|: ..|......::::||
 Frog     1 MAP----STDFLDQQKMTPKEKNKLRKPVVEKMRRDRINSSIEQLKGLLETVFHKQQPNVKLEKA 61

  Fly    61 EMLEAALVFMRKQV--VKQQAP-VSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHL 122
            ::||..:.::|:|.  :|.:.| .:.:.|| :|:||.....|:                      
 Frog    62 DILEMTVTYLRQQTLQIKSEIPHNNDIQMD-YKDGYSRCFEEV---------------------- 103

  Fly   123 GVEFQRMLQADQVQTSVTTSTPRPLSPASSGYHSDNEDSQS-AASPKPVEETMWRPW 178
             ::|..:.| .|.:|:...|.....:.|||........||| .|:......::||||
 Frog   104 -IDFLSLHQ-KQPETAKLISHFHSKATASSISSFPIRCSQSKTANGTGSSSSLWRPW 158

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)m5-HLHNP_524511.1 HLH 20..72 CDD:238036 16/52 (31%)
ORANGE 87..131 CDD:128787 6/43 (14%)
hes5.2NP_001037974.1 bHLH-O_HES5 20..77 CDD:381467 18/56 (32%)
ORANGE 90..128 CDD:128787 11/62 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 65 1.000 Inparanoid score I5183
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1378299at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.060

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